| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 95.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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121 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.9868 |
| MSRA | methionine sulfoxide reductase A | 4.75435 |
| MAMLD1 | mastermind-like domain containing 1 | 4.74895 |
| STAP2 | signal transducing adaptor family member 2 | 4.5581 |
| FGFR4 | fibroblast growth factor receptor 4 | 4.55735 |
| DENND2D | DENN/MADD domain containing 2D | 4.32895 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.3273 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.97615 |
| EPHB2 | EPH receptor B2 | 3.71051 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.6749 |
| ACLY | ATP citrate lyase | 3.42532 |
| GJB1 | gap junction protein, beta 1, 32kDa | 2.983 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 2.96215 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 2.94865 |
| MTM1 | myotubularin 1 | 2.72703 |
| AGMAT | agmatine ureohydrolase (agmatinase) | 2.6792 |
| COMP | cartilage oligomeric matrix protein | 2.6676 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.59125 |
| GSTM5 | glutathione S-transferase mu 5 | 2.5707 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.51412 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 2.5069 |
| GPA33 | glycoprotein A33 (transmembrane) | 2.45695 |
| CEP72 | centrosomal protein 72kDa | 2.45555 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 2.4374 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 2.41885 |
| TBXA2R | thromboxane A2 receptor | 2.40316 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.3869 |
| TRIM66 | tripartite motif containing 66 | 2.3594 |
| LYRM1 | LYR motif containing 1 | 2.3328 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | 2.3307 |
| TRIM36 | tripartite motif containing 36 | 2.3069 |
| GATA4 | GATA binding protein 4 | 2.296 |
| SAA4 | serum amyloid A4, constitutive | 2.25825 |
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) | 2.2348 |
| H2AJ | H2A.J histone | 2.22355 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 2.20658 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.1861 |
| NRBF2 | nuclear receptor binding factor 2 | 2.1498 |
| ZNF510 | zinc finger protein 510 | 2.144 |
| GIMAP5 | GTPase, IMAP family member 5 | 2.1296 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | 2.12595 |
| PIPOX | pipecolic acid oxidase | 2.1126 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 2.1124 |
| DOLK | dolichol kinase | 2.1075 |
| HSPA12A | heat shock 70kDa protein 12A | 2.10385 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | 2.10085 |
| IL1RAP | interleukin 1 receptor accessory protein | 2.08255 |
| PPIF | peptidylprolyl isomerase F | 2.07928 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 2.0788 |
| CDC37 | cell division cycle 37 | 2.0542 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 2.04877 |
| POMK | protein-O-mannose kinase | 2.04865 |
| ACRV1 | acrosomal vesicle protein 1 | 2.04819 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 2.04655 |
| DPF3 | D4, zinc and double PHD fingers, family 3 | 2.04225 |
| NTF3 | neurotrophin 3 | 2.0392 |
| BEAN1 | brain expressed, associated with NEDD4, 1 | 2.0389 |
| BLMH | bleomycin hydrolase | 2.0264 |
| ACP2 | acid phosphatase 2, lysosomal | 2.02435 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 2.023 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 2.01675 |
| CCDC7 | coiled-coil domain containing 7 | 2.00415 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 2.00125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBB6 | tubulin, beta 6 class V | -5.82105 |
| KIF20A | kinesin family member 20A | -5.7868 |
| COG2 | component of oligomeric golgi complex 2 | -4.98565 |
| PCNA | proliferating cell nuclear antigen | -4.66275 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -4.5095 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -4.42205 |
| JMJD6 | jumonji domain containing 6 | -3.78258 |
| MXRA7 | matrix-remodelling associated 7 | -3.7044 |
| TRAP1 | TNF receptor-associated protein 1 | -3.68175 |
| CBR3 | carbonyl reductase 3 | -3.4193 |
| KRT14 | keratin 14, type I | -3.27095 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -3.03135 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | -2.93965 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.80507 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) | -2.80325 |
| DDRGK1 | DDRGK domain containing 1 | -2.6596 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.6573 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.6565 |
| USP36 | ubiquitin specific peptidase 36 | -2.6298 |
| EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | -2.6051 |
| TXNDC15 | thioredoxin domain containing 15 | -2.59885 |
| RAB13 | RAB13, member RAS oncogene family | -2.57625 |
| SNTA1 | syntrophin, alpha 1 | -2.54595 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.4548 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.4474 |
| RAB38 | RAB38, member RAS oncogene family | -2.4459 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -2.3782 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | -2.37565 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.37225 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.36705 |
| AGTR1 | angiotensin II receptor, type 1 | -2.36155 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -2.34905 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -2.33085 |
| CTSG | cathepsin G | -2.30015 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -2.27905 |
| FSTL1 | follistatin-like 1 | -2.265 |
| SEC24A | SEC24 family member A | -2.22423 |
| H1-3 | H1.3 linker histone, cluster member | -2.22145 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.20535 |
| SRSF2 | serine/arginine-rich splicing factor 2 | -2.18397 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -2.1788 |
| PLTP | phospholipid transfer protein | -2.174 |
| TNRC6B | trinucleotide repeat containing 6B | -2.1632 |
| ANGPTL4 | angiopoietin-like 4 | -2.15815 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -2.14245 |
| RBM22 | RNA binding motif protein 22 | -2.1339 |
| SIPA1 | signal-induced proliferation-associated 1 | -2.1308 |
| ADI1 | acireductone dioxygenase 1 | -2.05345 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -2.04355 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -2.04305 |
| SIL1 | SIL1 nucleotide exchange factor | -2.0371 |
| DSTN | destrin (actin depolymerizing factor) | -2.03317 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -2.03105 |
| TMEM135 | transmembrane protein 135 | -2.02765 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -2.02723 |
| TYMS | thymidylate synthetase | -2.02452 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.0241 |
| RGS1 | regulator of G-protein signaling 1 | -2.00723 |
