CRCGN015_MCF10A.TP53.M_24H:L11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 32.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

56 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.7346
HBA1 hemoglobin, alpha 1 4.30415
KIF5C kinesin family member 5C 3.64828
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.3359
GATA2 GATA binding protein 2 3.20915
CHN1 chimerin 1 2.568
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.49205
COPS7A COP9 signalosome subunit 7A 2.42525
NPC1 Niemann-Pick disease, type C1 2.2745
CD9 CD9 molecule 2.24845
PECR peroxisomal trans-2-enoyl-CoA reductase 2.209
UGT8 UDP glycosyltransferase 8 2.2013
SATB1 SATB homeobox 1 2.1786
APIP APAF1 interacting protein 2.0906
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.04967
ADRB2 adrenoceptor beta 2, surface 2.0379
DEPDC1 DEP domain containing 1 2.02275
NOSIP nitric oxide synthase interacting protein 2.0203

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.18125
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.85165
NRIP1 nuclear receptor interacting protein 1 -4.32323
COG7 component of oligomeric golgi complex 7 -4.27215
CDC45 cell division cycle 45 -3.85465
MSMO1 methylsterol monooxygenase 1 -3.4264
PALB2 partner and localizer of BRCA2 -3.16265
KRT14 keratin 14, type I -3.0878
REEP5 receptor accessory protein 5 -2.80603
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.5176
BFAR bifunctional apoptosis regulator -2.50495
FLCN folliculin -2.4998
PDIA2 protein disulfide isomerase family A, member 2 -2.4302
IL10RB interleukin 10 receptor, beta -2.31325
TMEM268 transmembrane protein 268 -2.30385
CD320 CD320 molecule -2.2684
SPACA9 sperm acrosome associated 9 -2.2471
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.23542
MTERF3 mitochondrial transcription termination factor 3 -2.2159
TEX264 testis expressed 264 -2.21295
FAIM Fas apoptotic inhibitory molecule -2.2027
MBTD1 mbt domain containing 1 -2.18725
NUP107 nucleoporin 107kDa -2.16675
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.14675
ZNF426 zinc finger protein 426 -2.14595
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.13575
WDR26 WD repeat domain 26 -2.1286
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.12315
NINL ninein-like -2.07675
VPS35L VPS35 endosomal protein sorting factor like -2.0731
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.07095
ZNF559-ZNF177 ZNF559-ZNF177 readthrough -2.06065
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.04755
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.03395
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.0262
IL36A interleukin 36, alpha -2.01895
PPP4C protein phosphatase 4, catalytic subunit -2.0158
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.01365