CRCGN015_MCF10A.TP53.M_24H:L12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 10.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

48 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 10.0
CXCL2 chemokine (C-X-C motif) ligand 2 5.12865
ADAM10 ADAM metallopeptidase domain 10 4.97228
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.15485
ACAA1 acetyl-CoA acyltransferase 1 3.5386
KIF5C kinesin family member 5C 3.43145
MSRA methionine sulfoxide reductase A 2.8477
SATB1 SATB homeobox 1 2.83775
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.5894
GET1 guided entry of tail-anchored proteins factor 1 2.50405
NUP133 nucleoporin 133kDa 2.3977
TLCD3A TLC domain containing 3A 2.3954
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.3485
PRPF19 pre-mRNA processing factor 19 2.32345
VILL villin-like 2.27015
LDLRAP1 low density lipoprotein receptor adaptor protein 1 2.2639
GMIP GEM interacting protein 2.1618
CD164 CD164 molecule, sialomucin 2.10713
FXYD5 FXYD domain containing ion transport regulator 5 2.10385
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.1032
RBM28 RNA binding motif protein 28 2.0793
CETN3 centrin, EF-hand protein, 3 2.0393
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 2.03625
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.03465
ACO1 aconitase 1, soluble 2.02405
MTG1 mitochondrial ribosome-associated GTPase 1 2.0027

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.0306
TNIP1 TNFAIP3 interacting protein 1 -4.83285
HMG20B high mobility group 20B -4.73905
ENOPH1 enolase-phosphatase 1 -4.5931
LYPLA1 lysophospholipase I -4.2453
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.65035
STXBP2 syntaxin binding protein 2 -3.52915
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.9
DCK deoxycytidine kinase -2.7607
UBXN6 UBX domain protein 6 -2.6917
MPC2 mitochondrial pyruvate carrier 2 -2.59645
SEC24B SEC24 family member B -2.49385
TOM1L1 target of myb1 (chicken)-like 1 -2.3725
THSD1 thrombospondin, type I, domain containing 1 -2.3395
CCNG2 cyclin G2 -2.31
ZBED1 zinc finger, BED-type containing 1 -2.19315
UBXN2B UBX domain protein 2B -2.14555
MYRIP myosin VIIA and Rab interacting protein -2.1219
PIH1D1 PIH1 domain containing 1 -2.11685
GSE1 Gse1 coiled-coil protein -2.1109
CLSTN2 calsyntenin 2 -2.10895
CNOT8 CCR4-NOT transcription complex, subunit 8 -2.07398