| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | etodolac 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| OXSR1 | oxidative stress responsive 1 | 4.65505 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 3.8966 |
| KLHL9 | kelch-like family member 9 | 3.62955 |
| MELK | maternal embryonic leucine zipper kinase | 3.3817 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.37955 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.15982 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.88875 |
| STXBP1 | syntaxin binding protein 1 | 2.53245 |
| SMTN | smoothelin | 2.47253 |
| SATB1 | SATB homeobox 1 | 2.47055 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.41755 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.3767 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.25965 |
| SCAF8 | SR-related CTD-associated factor 8 | 2.2484 |
| BORCS6 | BLOC-1 related complex subunit 6 | 2.2199 |
| CRTAP | cartilage associated protein | 2.15535 |
| LYRM1 | LYR motif containing 1 | 2.1499 |
| MSRA | methionine sulfoxide reductase A | 2.14585 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.1159 |
| VWA1 | von Willebrand factor A domain containing 1 | 2.09795 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 2.0945 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 2.0911 |
| S100P | S100 calcium binding protein P | 2.08555 |
| RGS2 | regulator of G-protein signaling 2 | 2.06785 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 2.06505 |
| BLMH | bleomycin hydrolase | 2.06235 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.0563 |
| POGK | pogo transposable element with KRAB domain | 2.0397 |
| HBEGF | heparin-binding EGF-like growth factor | 2.02318 |
| SMAGP | small cell adhesion glycoprotein | 2.0215 |
| MPV17 | MpV17 mitochondrial inner membrane protein | 2.01825 |
| CYTL1 | cytokine-like 1 | 2.00445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSG2 | desmoglein 2 | -10.0 |
| HOXA5 | homeobox A5 | -6.8595 |
| NUP85 | nucleoporin 85kDa | -5.2836 |
| CHMP4B | charged multivesicular body protein 4B | -4.94058 |
| HSPA8 | heat shock 70kDa protein 8 | -4.34423 |
| TNIP1 | TNFAIP3 interacting protein 1 | -3.9658 |
| PRPF4 | pre-mRNA processing factor 4 | -3.9001 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.3768 |
| REEP5 | receptor accessory protein 5 | -3.11083 |
| ANXA2 | annexin A2 | -2.98158 |
| NGRN | neugrin, neurite outgrowth associated | -2.95495 |
| CCN6 | cellular communication network factor 6 | -2.8083 |
| HOXA4 | homeobox A4 | -2.50505 |
| USP6 | ubiquitin specific peptidase 6 | -2.39955 |
| TMEM94 | transmembrane protein 94 | -2.3849 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.3517 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | -2.31215 |
| TSPAN12 | tetraspanin 12 | -2.25715 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | -2.25035 |
| ZMYM2 | zinc finger, MYM-type 2 | -2.23267 |
| ACADL | acyl-CoA dehydrogenase, long chain | -2.21217 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.1747 |
| NOTCH4 | notch 4 | -2.1506 |
| UBAC1 | UBA domain containing 1 | -2.14975 |
| FANCF | Fanconi anemia, complementation group F | -2.1131 |
| HOXA7 | homeobox A7 | -2.09785 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -2.0925 |
| GRAMD1C | GRAM domain containing 1C | -2.0922 |
| NDST4 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 | -2.09115 |
| CNTRL | centriolin | -2.0906 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.08827 |
| LAMC3 | laminin, gamma 3 | -2.0782 |
| NEMP1 | nuclear envelope integral membrane protein 1 | -2.0728 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.07215 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -2.04993 |
| CASKIN2 | CASK interacting protein 2 | -2.04257 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | -2.02825 |
| ATP11B | ATPase, class VI, type 11B | -2.0238 |
| DROSHA | drosha, ribonuclease type III | -2.00915 |
| ZNF79 | zinc finger protein 79 | -2.0046 |
| CTXND1 | cortexin domain containing 1 | -2.00222 |
