| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,3-dibromo-1-propanol 100.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG4 | sperm associated antigen 4 | 10.0 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.9912 |
| LAGE3 | L antigen family, member 3 | 4.83405 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.3742 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 4.37005 |
| KLHL9 | kelch-like family member 9 | 3.84485 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.5411 |
| MELK | maternal embryonic leucine zipper kinase | 3.19085 |
| ATAD2B | ATPase family, AAA domain containing 2B | 2.53575 |
| EED | embryonic ectoderm development | 2.42805 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 2.33515 |
| FADS2 | fatty acid desaturase 2 | 2.3116 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.3031 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 2.2209 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 2.2113 |
| APTX | aprataxin | 2.18843 |
| TMEM164 | transmembrane protein 164 | 2.1764 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 2.1534 |
| ZWILCH | zwilch kinetochore protein | 2.12705 |
| COPS7A | COP9 signalosome subunit 7A | 2.11425 |
| VBP1 | von Hippel-Lindau binding protein 1 | 2.09635 |
| COPS5 | COP9 signalosome subunit 5 | 2.0739 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 2.07292 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2.06325 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 2.0542 |
| TMEM186 | transmembrane protein 186 | 2.0527 |
| BLMH | bleomycin hydrolase | 2.0474 |
| SLC10A3 | solute carrier family 10, member 3 | 2.03815 |
| PBK | PDZ binding kinase | 2.02135 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 2.00685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.33015 |
| RPA3 | replication protein A3, 14kDa | -5.23465 |
| RNF167 | ring finger protein 167 | -5.12355 |
| PGAM4 | phosphoglycerate mutase family member 4 | -4.74005 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -4.49825 |
| CD44 | CD44 molecule (Indian blood group) | -4.41145 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.71495 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.47155 |
| PANK2 | pantothenate kinase 2 | -2.7543 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.7114 |
| CFAP69 | cilia and flagella associated protein 69 | -2.58405 |
| ADD3 | adducin 3 (gamma) | -2.52781 |
| WBP1L | WW domain binding protein 1-like | -2.4738 |
| CD24 | CD24 molecule | -2.42771 |
| HAND2 | heart and neural crest derivatives expressed 2 | -2.2818 |
| CCDC81 | coiled-coil domain containing 81 | -2.2751 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.2275 |
| PROM1 | prominin 1 | -2.222 |
| ADGRG3 | adhesion G protein-coupled receptor G3 | -2.19675 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -2.1965 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.15562 |
| BSPRY | B-box and SPRY domain containing | -2.1228 |
| UBTD1 | ubiquitin domain containing 1 | -2.06325 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit | -2.0603 |
| GRN | granulin | -2.0338 |
| IMPACT | impact RWD domain protein | -2.02265 |
| TYMS | thymidylate synthetase | -2.01697 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | -2.01005 |
| MICU1 | mitochondrial calcium uptake 1 | -2.00555 |
