CRCGN015_MCF10A.TP53.M_24H:L17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 33.6 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 10.0
IDE insulin-degrading enzyme 5.46502
MOK MOK protein kinase 4.21315
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.90167
NOSIP nitric oxide synthase interacting protein 2.6513
LORICRIN loricrin cornified envelope precursor protein 2.35845
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.345
ERI2 ERI1 exoribonuclease family member 2 2.32085
CADM1 cell adhesion molecule 1 2.30952
KRT1 keratin 1, type II 2.30915
TYRP1 tyrosinase-related protein 1 2.2692
FLG filaggrin 2.18555
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.12025
CEP57 centrosomal protein 57kDa 2.10767
PECR peroxisomal trans-2-enoyl-CoA reductase 2.0854

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -5.219
PCNA proliferating cell nuclear antigen -5.0
HSPA1A heat shock 70kDa protein 1A -3.53175
CD58 CD58 molecule -3.47768
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.71623
TMEM230 transmembrane protein 230 -2.6885
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.5012
MTERF3 mitochondrial transcription termination factor 3 -2.47725
LOC112694756 uncharaterized LOC112694756 -2.4423
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.33475
ANXA2 annexin A2 -2.20823
KIN Kin17 DNA and RNA binding protein -2.1545
VCPKMT valosin containing protein lysine (K) methyltransferase -2.1008
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.02912
SNX5 sorting nexin 5 -2.0216
PLK3 polo-like kinase 3 -2.02095