CRCGN015_MCF10A.TP53.M_24H:L22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 98.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

53 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 5.33725
SSBP2 single-stranded DNA binding protein 2 5.0848
CCDC92 coiled-coil domain containing 92 4.85
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.4919
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 3.3175
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.17018
PPOX protoporphyrinogen oxidase 2.9054
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.67895
PLSCR1 phospholipid scramblase 1 2.66535
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.64155
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.5709
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.4796
CD69 CD69 molecule 2.44495
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.4218
SYT2 synaptotagmin II 2.41245
EVI2A ecotropic viral integration site 2A 2.40225
EVI2B ecotropic viral integration site 2B 2.4001
DENND2D DENN/MADD domain containing 2D 2.39095
DPF3 D4, zinc and double PHD fingers, family 3 2.3783
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 2.368
ZNF85 zinc finger protein 85 2.3197
AGR2 anterior gradient 2 2.3162
UGDH UDP-glucose 6-dehydrogenase 2.25625
AVEN apoptosis, caspase activation inhibitor 2.2515
SV2B synaptic vesicle glycoprotein 2B 2.24475
FOXF2 forkhead box F2 2.2279
PXMP2 peroxisomal membrane protein 2, 22kDa 2.20552
SASH3 SAM and SH3 domain containing 3 2.1661
CENPE centromere protein E, 312kDa 2.09805
CD3D CD3d molecule, delta (CD3-TCR complex) 2.09445
CD52 CD52 molecule 2.07382
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.04695
APOL6 apolipoprotein L, 6 2.0111
BCL2A1 BCL2-related protein A1 2.00995
FAM193B family with sequence similarity 193, member B 2.00505

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -5.67955
CTNND1 catenin (cadherin-associated protein), delta 1 -4.35577
ANKRD10 ankyrin repeat domain 10 -4.29865
YME1L1 YME1-like 1 ATPase -4.11998
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.72165
THAP11 THAP domain containing 11 -3.6258
SCRIB scribbled planar cell polarity protein -2.9275
SQSTM1 sequestosome 1 -2.70812
GAB2 GRB2-associated binding protein 2 -2.5526
STK25 serine/threonine kinase 25 -2.49325
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.38352
ZNF7 zinc finger protein 7 -2.34645
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.29665
GRAMD1C GRAM domain containing 1C -2.1273
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.10775
KIN Kin17 DNA and RNA binding protein -2.0957
SF3B2 splicing factor 3b, subunit 2, 145kDa -2.06685
GALK1 galactokinase 1 -2.03125