CRCGN015_MCF10A.TP53.M_24H:L24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 10.92 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INTS3 integrator complex subunit 3 6.0099
STAP2 signal transducing adaptor family member 2 5.62655
NOSIP nitric oxide synthase interacting protein 3.74145
SNX11 sorting nexin 11 3.6524
CNRIP1 cannabinoid receptor interacting protein 1 3.5239
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.50415
DENND2D DENN/MADD domain containing 2D 3.4393
KDM5D lysine (K)-specific demethylase 5D 3.05245
EVL Enah/Vasp-like 2.87015
SOCS2 suppressor of cytokine signaling 2 2.51183
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.44497
COG2 component of oligomeric golgi complex 2 2.44205
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.42523
SCAND1 SCAN domain containing 1 2.26545
CNPY3 canopy FGF signaling regulator 3 2.2464
CAPN1 calpain 1, (mu/I) large subunit 2.1476
ECSIT ECSIT signalling integrator 2.04595
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.03212

decreased expression

Symbol Name Standardized Value
TSPAN4 tetraspanin 4 -5.3691
RNF167 ring finger protein 167 -4.97735
KIF14 kinesin family member 14 -4.09815
MSN moesin -3.5765
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.23182
IGFBP7 insulin-like growth factor binding protein 7 -3.17215
SMC1A structural maintenance of chromosomes 1A -2.90852
RGS2 regulator of G-protein signaling 2 -2.6001
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.54495
KDM3A lysine (K)-specific demethylase 3A -2.4847
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.23663
TAC1 tachykinin, precursor 1 -2.1914
MTERF3 mitochondrial transcription termination factor 3 -2.1875
CORO1A coronin, actin binding protein, 1A -2.11925
NGRN neugrin, neurite outgrowth associated -2.10755
FGF4 fibroblast growth factor 4 -2.08355
MICB MHC class I polypeptide-related sequence B -2.07995
KDM5C lysine (K)-specific demethylase 5C -2.0667