CRCGN015_MCF10A.TP53.M_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitromethane 11.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBX2 T-box 2 4.30978
CHMP6 charged multivesicular body protein 6 3.78061
SNAP25 synaptosomal-associated protein, 25kDa 3.62735
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.41191
SSBP2 single-stranded DNA binding protein 2 3.38472
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.34342
CARMIL1 capping protein regulator and myosin 1 linker 1 3.22623
TRIM13 tripartite motif containing 13 3.19948
KLHL21 kelch-like family member 21 3.18251
ADGRE5 adhesion G protein-coupled receptor E5 2.8715
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.4264
GARRE1 granule associated Rac and RHOG effector 1 2.28364
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.25438
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.21384
FGL2 fibrinogen-like 2 2.1461
CSNK1A1 casein kinase 1, alpha 1 2.09975
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.09524
CD40 CD40 molecule, TNF receptor superfamily member 5 2.0383
ANAPC10 anaphase promoting complex subunit 10 2.03326

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -3.80669
YME1L1 YME1-like 1 ATPase -3.4812
CAB39 calcium binding protein 39 -3.39242
SLC25A46 solute carrier family 25, member 46 -3.31795
HMG20B high mobility group 20B -3.28706
TMEM109 transmembrane protein 109 -3.25739
ACAA1 acetyl-CoA acyltransferase 1 -3.14184
DERA deoxyribose-phosphate aldolase (putative) -2.96302
BLCAP bladder cancer associated protein -2.455
RPS5 ribosomal protein S5 -2.10052
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.08969
TRIP12 thyroid hormone receptor interactor 12 -2.05305