CRCGN015_MCF10A.TP53.M_24H:M04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethyl hydrogen phosphite 100.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 5.277
ADGRE5 adhesion G protein-coupled receptor E5 5.12255
STAP2 signal transducing adaptor family member 2 4.60595
SQOR sulfide quinone oxidoreductase 4.3377
HBB hemoglobin, beta 3.6648
HLA-DRA major histocompatibility complex, class II, DR alpha 3.65068
HBA1 hemoglobin, alpha 1 3.63028
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.2135
WIF1 WNT inhibitory factor 1 2.9873
SATB1 SATB homeobox 1 2.97095
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.7744
HSPA1A heat shock 70kDa protein 1A 2.3561
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.30915
TRAK2 trafficking protein, kinesin binding 2 2.3079
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.2541
CCDC85B coiled-coil domain containing 85B 2.20195
PYCR1 pyrroline-5-carboxylate reductase 1 2.07295
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.06365
CNRIP1 cannabinoid receptor interacting protein 1 2.03765

decreased expression

Symbol Name Standardized Value
DIPK1A divergent protein kinase domain 1A -5.0301
BAG3 BCL2-associated athanogene 3 -4.891
KIF14 kinesin family member 14 -4.69975
RAI14 retinoic acid induced 14 -3.7226
CANT1 calcium activated nucleotidase 1 -3.5071
PTK2 protein tyrosine kinase 2 -3.43173
BASP1 brain abundant, membrane attached signal protein 1 -2.9686
SOAT2 sterol O-acyltransferase 2 -2.83253
SDC1 syndecan 1 -2.53922
ANKRD10 ankyrin repeat domain 10 -2.2932
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -2.24045
PTPRK protein tyrosine phosphatase, receptor type, K -2.1876
OPRK1 opioid receptor, kappa 1 -2.18165
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.15085
HELZ helicase with zinc finger -2.08055
NALF1 NALCN channel auxiliary factor 1 -2.06255
GHRH growth hormone releasing hormone -2.00065