| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethyl hydrogen phosphite 11.14 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM5D | lysine (K)-specific demethylase 5D | 7.2282 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 6.4281 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 6.00412 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 5.64943 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.4091 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.2375 |
| CDCA4 | cell division cycle associated 4 | 5.22195 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.8484 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.78706 |
| ZFY | zinc finger protein, Y-linked | 3.70885 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.66647 |
| MTA2 | metastasis associated 1 family, member 2 | 3.60725 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.57428 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 3.30423 |
| NLGN4Y | neuroligin 4, Y-linked | 3.2312 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.9346 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.92155 |
| TPD52L2 | tumor protein D52-like 2 | 2.82325 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 2.57475 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.54673 |
| COPS7A | COP9 signalosome subunit 7A | 2.4593 |
| HBB | hemoglobin, beta | 2.37233 |
| WDR76 | WD repeat domain 76 | 2.331 |
| MDM4 | MDM4, p53 regulator | 2.3254 |
| RBBP5 | retinoblastoma binding protein 5 | 2.3218 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 2.287 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.2772 |
| LUM | lumican | 2.2365 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.16213 |
| HBA1 | hemoglobin, alpha 1 | 2.11646 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 2.0698 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.03225 |
| WDR43 | WD repeat domain 43 | 2.0113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMC1A | structural maintenance of chromosomes 1A | -6.37495 |
| KDM5C | lysine (K)-specific demethylase 5C | -6.16175 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -5.12095 |
| PUDP | pseudouridine 5'-phosphatase | -4.89035 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -4.694 |
| KDM6A | lysine (K)-specific demethylase 6A | -4.00013 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -3.85813 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.7963 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -3.74277 |
| PNPLA4 | patatin-like phospholipase domain containing 4 | -3.59425 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -2.93751 |
| CD320 | CD320 molecule | -2.65455 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.6075 |
| OFD1 | oral-facial-digital syndrome 1 | -2.5503 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.45475 |
| PIR | pirin (iron-binding nuclear protein) | -2.45475 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -2.38075 |
| PRSS22 | protease, serine, 22 | -2.3332 |
| RAB9A | RAB9A, member RAS oncogene family | -2.2743 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | -2.24055 |
| TMEM231 | transmembrane protein 231 | -2.14797 |
| SPA17 | sperm autoantigenic protein 17 | -2.1216 |
| CDK16 | cyclin-dependent kinase 16 | -2.09255 |
| SEPTIN6 | septin 6 | -2.07021 |
| CYTH2 | cytohesin 2 | -2.0331 |
| AGA | aspartylglucosaminidase | -2.0173 |
| STS | steroid sulfatase (microsomal), isozyme S | -2.00851 |
