CRCGN015_MCF10A.TP53.M_24H:M11 Gene Set
Genes
50 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
5.3464
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
5.1243
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
5.06625
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
4.70673
|
|
SPAG4
|
sperm associated antigen 4
|
4.37055
|
|
LGMN
|
legumain
|
4.10835
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
4.00565
|
|
USP9Y
|
ubiquitin specific peptidase 9, Y-linked
|
3.89217
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
3.3364
|
|
PRKCD
|
protein kinase C, delta
|
3.0966
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.9469
|
|
UTY
|
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
|
2.89743
|
|
CCNF
|
cyclin F
|
2.6362
|
|
WIF1
|
WNT inhibitory factor 1
|
2.45245
|
|
ZFY
|
zinc finger protein, Y-linked
|
2.3985
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.36465
|
|
OTUD3
|
OTU deubiquitinase 3
|
2.2177
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.17915
|
|
NLGN4Y
|
neuroligin 4, Y-linked
|
2.1305
|
|
TESK2
|
testis-specific kinase 2
|
2.1057
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.092
|
|
PCDHGA5
|
protocadherin gamma subfamily A, 5
|
2.05875
|
|
CFAP69
|
cilia and flagella associated protein 69
|
2.0126
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.9425
|
|
TEX10
|
testis expressed 10
|
-4.73265
|
|
THAP11
|
THAP domain containing 11
|
-4.5778
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-4.14162
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.79035
|
|
CLTB
|
clathrin, light chain B
|
-3.45266
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-3.4475
|
|
PUDP
|
pseudouridine 5'-phosphatase
|
-3.42965
|
|
KDM5C
|
lysine (K)-specific demethylase 5C
|
-3.1362
|
|
PRMT5
|
protein arginine methyltransferase 5
|
-3.04825
|
|
CYREN
|
cell cycle regulator of NHEJ
|
-2.9965
|
|
PSMB5
|
proteasome (prosome, macropain) subunit, beta type, 5
|
-2.69385
|
|
LOC124905557
|
eukaryotic translation initiation factor 1A, X-chromosomal
|
-2.67859
|
|
THTPA
|
thiamine triphosphatase
|
-2.6318
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.5334
|
|
UBA1
|
ubiquitin-like modifier activating enzyme 1
|
-2.50725
|
|
ZRSR2
|
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
|
-2.4944
|
|
KDM6A
|
lysine (K)-specific demethylase 6A
|
-2.38835
|
|
STX5
|
syntaxin 5
|
-2.30675
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.30557
|
|
COPZ2
|
coatomer protein complex, subunit zeta 2
|
-2.22395
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.1111
|
|
USP9X
|
ubiquitin specific peptidase 9, X-linked
|
-2.09085
|
|
APBB1IP
|
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
|
-2.07045
|
|
P2RX4
|
purinergic receptor P2X, ligand gated ion channel, 4
|
-2.0697
|
|
DSG3
|
desmoglein 3
|
-2.043
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.0397
|
