CRCGN015_MCF10A.TP53.M_24H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 5.15592
CNPY3 canopy FGF signaling regulator 3 5.01965
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 3.89465
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.7708
ACAA1 acetyl-CoA acyltransferase 1 3.4612
AAMDC adipogenesis associated, Mth938 domain containing 3.0857
AGR2 anterior gradient 2 3.0824
CNRIP1 cannabinoid receptor interacting protein 1 3.01095
TIAM1 T-cell lymphoma invasion and metastasis 1 2.90522
PKN1 protein kinase N1 2.90477
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.66615
PDLIM1 PDZ and LIM domain 1 2.6028
THAP12 THAP domain containing 12 2.36985
ADRB2 adrenoceptor beta 2, surface 2.3386
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.3339
ADCY7 adenylate cyclase 7 2.3321
REV1 REV1, polymerase (DNA directed) 2.27745
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.22485
TATDN2 TatD DNase domain containing 2 2.2055
OLFML2B olfactomedin-like 2B 2.1694
SNRPF small nuclear ribonucleoprotein polypeptide F 2.1673
MAST2 microtubule associated serine/threonine kinase 2 2.16592
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 2.11555
CKAP5 cytoskeleton associated protein 5 2.0753
EVL Enah/Vasp-like 2.0742

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -5.4245
HMG20B high mobility group 20B -5.25405
HAT1 histone acetyltransferase 1 -4.738
CTNND1 catenin (cadherin-associated protein), delta 1 -4.67223
CANT1 calcium activated nucleotidase 1 -4.56693
FASTKD5 FAST kinase domains 5 -4.46
VDAC1 voltage-dependent anion channel 1 -4.30472
YME1L1 YME1-like 1 ATPase -3.9113
LOC127933115 uncharacterized LOC127933115 -3.01265
PERP PERP, TP53 apoptosis effector -2.7532
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.59275
SYNGR2 synaptogyrin 2 -2.49795
SIL1 SIL1 nucleotide exchange factor -2.33425
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -2.30515
KRT14 keratin 14, type I -2.3017
IFT22 intraflagellar transport 22 -2.26035
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.16685
TXNDC15 thioredoxin domain containing 15 -2.1148
MMRN2 multimerin 2 -2.11365
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 -2.09565
ADAMDEC1 ADAM-like, decysin 1 -2.08845
CD9 CD9 molecule -2.05335
PRDX4 peroxiredoxin 4 -2.0351
ATF3 activating transcription factor 3 -2.0308
PRICKLE3 prickle homolog 3 (Drosophila) -2.0078
RTL10 retrotransposon Gag like 10 -2.0018