CRCGN015_MCF10A.TP53.M_24H:M15 Gene Set
Genes
55 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STAP2
|
signal transducing adaptor family member 2
|
5.2953
|
|
HBA1
|
hemoglobin, alpha 1
|
4.77768
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
4.5359
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
3.91875
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
3.54402
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
3.53035
|
|
HOXA5
|
homeobox A5
|
3.25095
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
3.20937
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.19333
|
|
HBB
|
hemoglobin, beta
|
2.61747
|
|
NMD3
|
NMD3 ribosome export adaptor
|
2.53065
|
|
TBPL1
|
TBP-like 1
|
2.38635
|
|
SCAND1
|
SCAN domain containing 1
|
2.3464
|
|
NRIP3
|
nuclear receptor interacting protein 3
|
2.23085
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.22365
|
|
USP9Y
|
ubiquitin specific peptidase 9, Y-linked
|
2.21947
|
|
HEBP1
|
heme binding protein 1
|
2.1555
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
2.1232
|
|
NOC3L
|
nucleolar complex associated 3 homolog (S. cerevisiae)
|
2.12275
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.1213
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
2.0872
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.08295
|
|
RLIG1
|
RNA 5'-phosphate and 3'-OH ligase 1
|
2.0404
|
|
IVL
|
involucrin
|
2.0232
|
|
MAPKAP1
|
mitogen-activated protein kinase associated protein 1
|
2.0051
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.0046
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PMM2
|
phosphomannomutase 2
|
-4.7554
|
|
DSG2
|
desmoglein 2
|
-4.68655
|
|
CCNB1
|
cyclin B1
|
-4.43245
|
|
GNAS
|
GNAS complex locus
|
-4.12378
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-3.81857
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-3.78795
|
|
STXBP2
|
syntaxin binding protein 2
|
-3.7601
|
|
THAP11
|
THAP domain containing 11
|
-3.61245
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.4846
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.61235
|
|
PGAP6
|
post-GPI attachment to proteins 6
|
-2.50965
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.41963
|
|
KDM5C
|
lysine (K)-specific demethylase 5C
|
-2.37665
|
|
ADRA2A
|
adrenoceptor alpha 2A
|
-2.3698
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.34557
|
|
ZRSR2
|
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
|
-2.3434
|
|
HCK
|
HCK proto-oncogene, Src family tyrosine kinase
|
-2.298
|
|
INS
|
insulin
|
-2.2889
|
|
KDM6A
|
lysine (K)-specific demethylase 6A
|
-2.16475
|
|
USP9X
|
ubiquitin specific peptidase 9, X-linked
|
-2.1387
|
|
NKAPD1
|
NKAP domain containing 1
|
-2.1376
|
|
IGF2
|
insulin-like growth factor 2
|
-2.13687
|
|
SEPHS2
|
selenophosphate synthetase 2
|
-2.07825
|
|
SERPINA4
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
|
-2.06565
|
|
RAB4B
|
RAB4B, member RAS oncogene family
|
-2.0521
|
|
ATP5F1E
|
ATP synthase F1 subunit epsilon
|
-2.04705
|
|
CTRL
|
chymotrypsin-like
|
-2.0378
|
|
MUC16
|
mucin 16, cell surface associated
|
-2.0266
|
|
AGGF1
|
angiogenic factor with G patch and FHA domains 1
|
-2.01365
|
