| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cadmium chloride 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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146 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 10.0 |
| HBA1 | hemoglobin, alpha 1 | 5.70269 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 5.31005 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 5.0327 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.96815 |
| MSRA | methionine sulfoxide reductase A | 4.72875 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.36355 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.9889 |
| TBX2 | T-box 2 | 3.9124 |
| TXNRD1 | thioredoxin reductase 1 | 3.7413 |
| KLHL9 | kelch-like family member 9 | 3.65922 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.6517 |
| COMP | cartilage oligomeric matrix protein | 3.60145 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.5277 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.1132 |
| TUBB6 | tubulin, beta 6 class V | 2.98095 |
| ABHD4 | abhydrolase domain containing 4 | 2.7814 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 2.75285 |
| TBXA2R | thromboxane A2 receptor | 2.74195 |
| STAMBP | STAM binding protein | 2.7154 |
| OXSR1 | oxidative stress responsive 1 | 2.62875 |
| CENPE | centromere protein E, 312kDa | 2.6014 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 2.59895 |
| CD34 | CD34 molecule | 2.5982 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 2.5738 |
| ATG4A | autophagy related 4A, cysteine peptidase | 2.57155 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.55325 |
| POU4F1 | POU class 4 homeobox 1 | 2.54772 |
| CD5L | CD5 molecule-like | 2.50835 |
| HBB | hemoglobin, beta | 2.48873 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 2.47255 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.42295 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.40838 |
| ALX1 | ALX homeobox 1 | 2.3797 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.37335 |
| SELENBP1 | selenium binding protein 1 | 2.3646 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 2.35025 |
| SDCBP | syndecan binding protein (syntenin) | 2.3262 |
| NECAP1 | NECAP endocytosis associated 1 | 2.3147 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 2.2846 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 2.2468 |
| H2BC12 | H2B clustered histone 12 | 2.21 |
| WDR73 | WD repeat domain 73 | 2.1999 |
| TSPAN7 | tetraspanin 7 | 2.18735 |
| OLFM4 | olfactomedin 4 | 2.1714 |
| EED | embryonic ectoderm development | 2.17115 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | 2.1707 |
| ATF3 | activating transcription factor 3 | 2.1602 |
| ADIPOR1 | adiponectin receptor 1 | 2.15935 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 2.15695 |
| PRR13 | proline rich 13 | 2.1554 |
| RRAS | related RAS viral (r-ras) oncogene homolog | 2.15305 |
| MAOB | monoamine oxidase B | 2.14595 |
| MXRA8 | matrix-remodelling associated 8 | 2.1455 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 2.14195 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 2.12605 |
| MSRB1 | methionine sulfoxide reductase B1 | 2.12325 |
| EXOC1 | exocyst complex component 1 | 2.1226 |
| BAALC | brain and acute leukemia, cytoplasmic | 2.11865 |
| DCTN1 | dynactin 1 | 2.10978 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 | 2.10535 |
| CTBP2 | C-terminal binding protein 2 | 2.09445 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 2.09405 |
| PM20D1 | peptidase M20 domain containing 1 | 2.08498 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 2.07595 |
| HAGH | hydroxyacylglutathione hydrolase | 2.07235 |
| HSPA1A | heat shock 70kDa protein 1A | 2.05735 |
| RASL12 | RAS-like, family 12 | 2.04705 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 2.03645 |
| CCDC85B | coiled-coil domain containing 85B | 2.036 |
| USP18 | ubiquitin specific peptidase 18 | 2.0349 |
| MTTP | microsomal triglyceride transfer protein | 2.03195 |
| PIR | pirin (iron-binding nuclear protein) | 2.02975 |
| CD99 | CD99 molecule | 2.02698 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 2.02085 |
| PTK2 | protein tyrosine kinase 2 | 2.01292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TOR1A | torsin family 1, member A (torsin A) | -6.4026 |
| PCNA | proliferating cell nuclear antigen | -5.49155 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -5.1085 |
| HSPA8 | heat shock 70kDa protein 8 | -5.09227 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.2522 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -4.2333 |
| NLRP4 | NLR family, pyrin domain containing 4 | -3.9138 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.70165 |
| ANKRD10 | ankyrin repeat domain 10 | -3.37815 |
| OXTR | oxytocin receptor | -3.2918 |
| ENTR1 | endosome associated trafficking regulator 1 | -3.24655 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -3.084 |
| NNT | nicotinamide nucleotide transhydrogenase | -3.04833 |
| EXOSC4 | exosome component 4 | -2.91505 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.8765 |
| ANKRD36C | ankyrin repeat domain 36C | -2.75385 |
| MAP6D1 | MAP6 domain containing 1 | -2.62325 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -2.57795 |
| JADE1 | jade family PHD finger 1 | -2.4856 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.4703 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.45267 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -2.43455 |
| KIF14 | kinesin family member 14 | -2.42715 |
| RBMX2 | RNA binding motif protein, X-linked 2 | -2.4201 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -2.41095 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | -2.39337 |
| AK8 | adenylate kinase 8 | -2.38335 |
| SUSD6 | sushi domain containing 6 | -2.36635 |
| FPGS | folylpolyglutamate synthase | -2.36535 |
| CTNNBIP1 | catenin, beta interacting protein 1 | -2.35455 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -2.3498 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | -2.3461 |
| GOLGA8A | golgin A8 family, member A | -2.3274 |
| NUP210 | nucleoporin 210kDa | -2.32386 |
| VEGFC | vascular endothelial growth factor C | -2.32085 |
| TOR1B | torsin family 1, member B (torsin B) | -2.2887 |
| NLK | nemo-like kinase | -2.2844 |
| CCL23 | chemokine (C-C motif) ligand 23 | -2.27472 |
| DDRGK1 | DDRGK domain containing 1 | -2.2624 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -2.2591 |
| KMT5A | lysine methyltransferase 5A | -2.25835 |
| RAB3D | RAB3D, member RAS oncogene family | -2.2442 |
| TYMS | thymidylate synthetase | -2.24132 |
| PUS3 | pseudouridylate synthase 3 | -2.241 |
| TMEM94 | transmembrane protein 94 | -2.23455 |
| PIH1D1 | PIH1 domain containing 1 | -2.2238 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.20275 |
| USP20 | ubiquitin specific peptidase 20 | -2.1712 |
| WDR55 | WD repeat domain 55 | -2.15895 |
| CCNL2 | cyclin L2 | -2.14925 |
| ZNF428 | zinc finger protein 428 | -2.14805 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -2.13065 |
| MVB12B | multivesicular body subunit 12B | -2.11913 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -2.11855 |
| RLIM | ring finger protein, LIM domain interacting | -2.1164 |
| REV1 | REV1, polymerase (DNA directed) | -2.1154 |
| STX11 | syntaxin 11 | -2.11525 |
| URM1 | ubiquitin related modifier 1 | -2.10955 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -2.09995 |
| CTSG | cathepsin G | -2.08315 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -2.07645 |
| ZNF93 | zinc finger protein 93 | -2.06665 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -2.06222 |
| MED24 | mediator complex subunit 24 | -2.04325 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | -2.0306 |
| PAQR4 | progestin and adipoQ receptor family member IV | -2.0254 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -2.0172 |
| RNF113A | ring finger protein 113A | -2.0032 |
| STX5 | syntaxin 5 | -2.0029 |
| GRAMD4 | GRAM domain containing 4 | -2.00035 |
