CRCGN015_MCF10A.TP53.M_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 32.62 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.1621
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.1033
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.0889
FGFR4 fibroblast growth factor receptor 4 4.06188
VGLL4 vestigial-like family member 4 4.0227
KIF5C kinesin family member 5C 4.01155
MAST2 microtubule associated serine/threonine kinase 2 3.70778
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.69955
CHN1 chimerin 1 3.22135
COMP cartilage oligomeric matrix protein 3.16775
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.9994
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.7181
GADD45A growth arrest and DNA-damage-inducible, alpha 2.62355
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.55305
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.397
ZNF652 zinc finger protein 652 2.39085
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.3635
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.32015
PLS3 plastin 3 2.1852
PECR peroxisomal trans-2-enoyl-CoA reductase 2.13765
VIL1 villin 1 2.132
BAMBI BMP and activin membrane-bound inhibitor 2.1141
F2R coagulation factor II (thrombin) receptor 2.1112
ZNF573 zinc finger protein 573 2.09985
TLCD3A TLC domain containing 3A 2.07755
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.06785
ARMC1 armadillo repeat containing 1 2.00515

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.3407
TCTA T-cell leukemia translocation altered -4.1889
GRN granulin -3.49345
TOR1A torsin family 1, member A (torsin A) -3.4013
GRWD1 glutamate-rich WD repeat containing 1 -2.81945
DCK deoxycytidine kinase -2.6687
FBXO7 F-box protein 7 -2.58955
BASP1 brain abundant, membrane attached signal protein 1 -2.5323
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.29885
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.12217
TMPRSS11D transmembrane protease, serine 11D -2.11115
INTS3 integrator complex subunit 3 -2.0344
AQP3 aquaporin 3 (Gill blood group) -2.00043