CRCGN015_MCF10A.TP53.M_24H:N01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 104.79 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 4.05127
CCDC92 coiled-coil domain containing 92 3.78542
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.53594
GATA3 GATA binding protein 3 3.33762
SPAG4 sperm associated antigen 4 3.33702
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.10556
PRR7 proline rich 7 (synaptic) 2.93139
MCUR1 mitochondrial calcium uniporter regulator 1 2.84425
GPER1 G protein-coupled estrogen receptor 1 2.69701
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.50889
SYNGAP1 synaptic Ras GTPase activating protein 1 2.44288
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.20909
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.18823
CNRIP1 cannabinoid receptor interacting protein 1 2.14423
CNPY3 canopy FGF signaling regulator 3 2.11056
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.07535

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -3.87276
DYNLT3 dynein, light chain, Tctex-type 3 -3.36894
TRAPPC3 trafficking protein particle complex 3 -2.88437
CCNB1 cyclin B1 -2.83991
BPHL biphenyl hydrolase-like (serine hydrolase) -2.81277
TXNDC9 thioredoxin domain containing 9 -2.76288
TUBB6 tubulin, beta 6 class V -2.16559
DERL2 derlin 2 -2.07717
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.04953
NUP88 nucleoporin 88kDa -2.02716