CRCGN015_MCF10A.TP53.M_24H:N03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 11.64 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 5.0077
ALDOC aldolase C, fructose-bisphosphate 4.55858
KDM5D lysine (K)-specific demethylase 5D 4.28145
CARMIL1 capping protein regulator and myosin 1 linker 1 4.05638
CHMP6 charged multivesicular body protein 6 3.88925
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.48415
HBB hemoglobin, beta 3.39089
STAMBP STAM binding protein 3.30169
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.24963
METRN meteorin, glial cell differentiation regulator 3.16313
HBA1 hemoglobin, alpha 1 3.12601
COQ8A coenzyme Q8A 2.99845
SPAG4 sperm associated antigen 4 2.91116
HYOU1 hypoxia up-regulated 1 2.82774
CNRIP1 cannabinoid receptor interacting protein 1 2.72061
USP9Y ubiquitin specific peptidase 9, Y-linked 2.69567
OXSR1 oxidative stress responsive 1 2.67784
SYNGAP1 synaptic Ras GTPase activating protein 1 2.67537
TPD52L2 tumor protein D52-like 2 2.36364
IMMT inner membrane protein, mitochondrial 2.33594
RAB1B RAB1B, member RAS oncogene family 2.23141
CSNK1A1 casein kinase 1, alpha 1 2.18834
ACBD3 acyl-CoA binding domain containing 3 2.05381

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.03052
HOXA5 homeobox A5 -3.96821
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.78363
KDM5C lysine (K)-specific demethylase 5C -3.69604
TOR1A torsin family 1, member A (torsin A) -3.33935
SMC1A structural maintenance of chromosomes 1A -3.07725
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -3.03185
ATP11B ATPase, class VI, type 11B -2.8318
ACAA1 acetyl-CoA acyltransferase 1 -2.78645
COTL1 coactosin-like F-actin binding protein 1 -2.73606
BPHL biphenyl hydrolase-like (serine hydrolase) -2.67149
PUDP pseudouridine 5'-phosphatase -2.5941
RGS2 regulator of G-protein signaling 2 -2.52498
HSPA1A heat shock 70kDa protein 1A -2.36505
PCNA proliferating cell nuclear antigen -2.32652
CDC37L1 cell division cycle 37-like 1 -2.1586
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.15257
FPGS folylpolyglutamate synthase -2.13054
TMEM115 transmembrane protein 115 -2.09202
CD69 CD69 molecule -2.03544