CRCGN015_MCF10A.TP53.M_24H:N04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.39552
GADD45A growth arrest and DNA-damage-inducible, alpha 3.19008
CNRIP1 cannabinoid receptor interacting protein 1 3.01407
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.73513
SATB1 SATB homeobox 1 2.62609
AGR2 anterior gradient 2 2.07365

decreased expression

Symbol Name Standardized Value
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.32192
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.31254
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.80205
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.21289
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.14352
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.12078
COTL1 coactosin-like F-actin binding protein 1 -2.60193
SGK1 serum/glucocorticoid regulated kinase 1 -2.45201
CD81 CD81 molecule -2.37775
FPGS folylpolyglutamate synthase -2.28238
CCDC86 coiled-coil domain containing 86 -2.26191
BASP1 brain abundant, membrane attached signal protein 1 -2.20224
LYPLA1 lysophospholipase I -2.1553