CRCGN015_MCF10A.TP53.M_24H:N07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyl nitrite 96.31 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 5.5203
STIMATE STIM activating enhancer 5.39055
FZD1 frizzled class receptor 1 3.93202
ACAA1 acetyl-CoA acyltransferase 1 3.5656
CERK ceramide kinase 3.19255
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.5222
CHN1 chimerin 1 2.45315
ACLY ATP citrate lyase 2.1772
IGFBP3 insulin-like growth factor binding protein 3 2.1171
UBA5 ubiquitin-like modifier activating enzyme 5 2.02585

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -4.46795
KRT14 keratin 14, type I -3.7114
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.62975
PCCB propionyl CoA carboxylase, beta polypeptide -2.9237
DYNLT3 dynein, light chain, Tctex-type 3 -2.75965
CBR3 carbonyl reductase 3 -2.6649
SQSTM1 sequestosome 1 -2.56148
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.5363
CD320 CD320 molecule -2.4481
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.0627
PHACTR1 phosphatase and actin regulator 1 -2.05395
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.0087
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.0007