| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isobutyl nitrite 32.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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129 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 5.2226 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.07053 |
| ADAM10 | ADAM metallopeptidase domain 10 | 4.83535 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.68513 |
| MAP7 | microtubule-associated protein 7 | 4.68263 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.6246 |
| GATA3 | GATA binding protein 3 | 4.50308 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.72253 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.16853 |
| RSPH10B2 | radial spoke head 10 homolog B2 (Chlamydomonas) | 3.02365 |
| CRTC3 | CREB regulated transcription coactivator 3 | 2.91265 |
| GCC1 | GRIP and coiled-coil domain containing 1 | 2.90455 |
| NUP205 | nucleoporin 205kDa | 2.8626 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 2.66843 |
| PDLIM1 | PDZ and LIM domain 1 | 2.65745 |
| DCAF17 | DDB1 and CUL4 associated factor 17 | 2.5524 |
| ZNF510 | zinc finger protein 510 | 2.53445 |
| PCNA | proliferating cell nuclear antigen | 2.5179 |
| CD5 | CD5 molecule | 2.49565 |
| HELZ | helicase with zinc finger | 2.40645 |
| WDR4 | WD repeat domain 4 | 2.4031 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | 2.402 |
| EDF1 | endothelial differentiation-related factor 1 | 2.3762 |
| NIT2 | nitrilase family, member 2 | 2.3741 |
| ZBED5 | zinc finger, BED-type containing 5 | 2.36955 |
| RBM28 | RNA binding motif protein 28 | 2.354 |
| ZNF267 | zinc finger protein 267 | 2.31345 |
| SOX15 | SRY (sex determining region Y)-box 15 | 2.28045 |
| HBB | hemoglobin, beta | 2.27838 |
| LRRN3 | leucine rich repeat neuronal 3 | 2.2741 |
| REEP4 | receptor accessory protein 4 | 2.2741 |
| SLC35H1 | solute carrier family 35 member H1 | 2.27045 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 2.2633 |
| PMP2 | peripheral myelin protein 2 | 2.25405 |
| MACIR | macrophage immunometabolism regulator | 2.2147 |
| TRIM32 | tripartite motif containing 32 | 2.2129 |
| S100PBP | S100P binding protein | 2.1999 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 2.19922 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 2.1849 |
| LIPC | lipase, hepatic | 2.17375 |
| RAB5IF | RAB5 interacting factor | 2.17315 |
| TLCD3A | TLC domain containing 3A | 2.1638 |
| TULP4 | tubby like protein 4 | 2.13505 |
| ATOX1 | antioxidant 1 copper chaperone | 2.13275 |
| URM1 | ubiquitin related modifier 1 | 2.128 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.12745 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 2.11945 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 2.11635 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 2.10955 |
| RNF113A | ring finger protein 113A | 2.10395 |
| CYREN | cell cycle regulator of NHEJ | 2.1012 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | 2.08435 |
| OLFML2B | olfactomedin-like 2B | 2.07245 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | 2.0711 |
| SCAND1 | SCAN domain containing 1 | 2.0535 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.048 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 2.04355 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 2.04168 |
| DUS2 | dihydrouridine synthase 2 | 2.03867 |
| RBL1 | retinoblastoma-like 1 | 2.03305 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 2.0319 |
| KRT33B | keratin 33B, type I | 2.0311 |
| CHL1 | cell adhesion molecule L1-like | 2.0155 |
| PTER | phosphotriesterase related | 2.00465 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 2.00215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP4B | charged multivesicular body protein 4B | -5.03235 |
| CDC20 | cell division cycle 20 | -5.0 |
| STMN1 | stathmin 1 | -4.34575 |
| STXBP2 | syntaxin binding protein 2 | -3.90945 |
| HTRA1 | HtrA serine peptidase 1 | -3.1068 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.94878 |
| PLA1A | phospholipase A1 member A | -2.82175 |
| GMPR | guanosine monophosphate reductase | -2.7583 |
| LRRC42 | leucine rich repeat containing 42 | -2.7078 |
| NMU | neuromedin U | -2.688 |
| TKT | transketolase | -2.68333 |
| CUEDC1 | CUE domain containing 1 | -2.6458 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | -2.55205 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.5424 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | -2.52095 |
| TCEAL9 | transcription elongation factor A like 9 | -2.51625 |
| FAIM | Fas apoptotic inhibitory molecule | -2.4429 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | -2.432 |
| BLNK | B-cell linker | -2.4025 |
| RNASE6 | ribonuclease, RNase A family, k6 | -2.38855 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -2.38555 |
| FBRS | fibrosin | -2.38415 |
| EEF1AKMT3 | EEF1A lysine methyltransferase 3 | -2.37875 |
| CNN3 | calponin 3, acidic | -2.36705 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.34 |
| MED8 | mediator complex subunit 8 | -2.33842 |
| CPM | carboxypeptidase M | -2.33445 |
| PDGFD | platelet derived growth factor D | -2.3084 |
| METTL25B | methyltransferase like 25B | -2.29845 |
| HDAC5 | histone deacetylase 5 | -2.29555 |
| XK | X-linked Kx blood group | -2.272 |
| BBOF1 | basal body orientation factor 1 | -2.25 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -2.243 |
| PHF1 | PHD finger protein 1 | -2.24088 |
| FOXK2 | forkhead box K2 | -2.22925 |
| NINL | ninein-like | -2.21865 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | -2.2138 |
| LEFTY1 | left-right determination factor 1 | -2.201 |
| CKB | creatine kinase, brain | -2.17935 |
| VASP | vasodilator-stimulated phosphoprotein | -2.1524 |
| MRPL37 | mitochondrial ribosomal protein L37 | -2.1429 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | -2.11645 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -2.1155 |
| LRRC17 | leucine rich repeat containing 17 | -2.1142 |
| KATNIP | katanin interacting protein | -2.11 |
| GID8 | GID complex subunit 8 | -2.103 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -2.10095 |
| SPARCL1 | SPARC-like 1 (hevin) | -2.0929 |
| EMC3 | ER membrane protein complex subunit 3 | -2.08925 |
| SZT2 | seizure threshold 2 homolog (mouse) | -2.0852 |
| TOE1 | target of EGR1, member 1 (nuclear) | -2.05185 |
| H1-2 | H1.2 linker histone, cluster member | -2.0388 |
| DDN | dendrin | -2.03855 |
| PLPP6 | phospholipid phosphatase 6 | -2.0359 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -2.0278 |
| H1-0 | H1.0 linker histone | -2.02065 |
| NPTX1 | neuronal pentraxin I | -2.01905 |
| ARG2 | arginase 2 | -2.01557 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) | -2.01235 |
| HOXB2 | homeobox B2 | -2.01235 |
| VPS35L | VPS35 endosomal protein sorting factor like | -2.0109 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 | -2.0089 |
| MARCHF2 | membrane associated ring-CH-type finger 2 | -2.00055 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | -2.00025 |
