CRCGN015_MCF10A.TP53.M_24H:N09 Gene Set
Genes
51 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.15275
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.49845
|
|
KIF5C
|
kinesin family member 5C
|
3.84973
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.08547
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.9821
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.787
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.7053
|
|
SPDEF
|
SAM pointed domain containing ETS transcription factor
|
2.54342
|
|
FKBP5
|
FK506 binding protein 5
|
2.4983
|
|
MAEA
|
macrophage erythroblast attacher
|
2.4861
|
|
B4GALT2
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
|
2.4337
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.42435
|
|
FPGS
|
folylpolyglutamate synthase
|
2.2853
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.25215
|
|
ACIN1
|
apoptotic chromatin condensation inducer 1
|
2.2161
|
|
U2AF2
|
U2 small nuclear RNA auxiliary factor 2
|
2.19395
|
|
CRIPTO3
|
cripto, EGF-CFC family member 3
|
2.1501
|
|
MUC6
|
mucin 6, oligomeric mucus/gel-forming
|
2.0857
|
|
CDK9
|
cyclin-dependent kinase 9
|
2.08155
|
|
MAP3K10
|
mitogen-activated protein kinase kinase kinase 10
|
2.0482
|
|
PPP2R1A
|
protein phosphatase 2, regulatory subunit A, alpha
|
2.03895
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UFM1
|
ubiquitin-fold modifier 1
|
-5.525
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-4.80737
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.50445
|
|
STXBP2
|
syntaxin binding protein 2
|
-4.45075
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-4.15732
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.8771
|
|
ABI1
|
abl-interactor 1
|
-3.17763
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-3.03913
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.03737
|
|
STX12
|
syntaxin 12
|
-2.76935
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-2.5978
|
|
DDX1
|
DEAD (Asp-Glu-Ala-Asp) box helicase 1
|
-2.462
|
|
MRPS15
|
mitochondrial ribosomal protein S15
|
-2.42215
|
|
NCKAP1
|
NCK-associated protein 1
|
-2.39605
|
|
STAM
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
|
-2.3913
|
|
PLSCR4
|
phospholipid scramblase 4
|
-2.3847
|
|
TVP23B
|
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
|
-2.34605
|
|
TTC28
|
tetratricopeptide repeat domain 28
|
-2.27227
|
|
AZIN2
|
antizyme inhibitor 2
|
-2.25885
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.21965
|
|
MTPAP
|
mitochondrial poly(A) polymerase
|
-2.2144
|
|
NDUFA10
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
|
-2.20255
|
|
TMX2
|
thioredoxin-related transmembrane protein 2
|
-2.1923
|
|
AGO1
|
argonaute RISC catalytic component 1
|
-2.10105
|
|
FAM8A1
|
family with sequence similarity 8, member A1
|
-2.09995
|
|
MTX2
|
metaxin 2
|
-2.09965
|
|
PRPF18
|
pre-mRNA processing factor 18
|
-2.0969
|
|
FBXO3
|
F-box protein 3
|
-2.0964
|
|
DMXL1
|
Dmx-like 1
|
-2.08115
|
|
COL8A2
|
collagen, type VIII, alpha 2
|
-2.01018
|
