CRCGN015_MCF10A.TP53.M_24H:N12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetranitromethane 11.26 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.65095
TBX2 T-box 2 3.90615
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.611
AXIN1 axin 1 3.46915
NOSIP nitric oxide synthase interacting protein 3.27475
GRB10 growth factor receptor-bound protein 10 3.15763
DENND2D DENN/MADD domain containing 2D 2.34985
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.33575
FOS FBJ murine osteosarcoma viral oncogene homolog 2.224
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 2.1447
IGFBP3 insulin-like growth factor binding protein 3 2.1193

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.47095
MTERF3 mitochondrial transcription termination factor 3 -2.7766
PSRC1 proline/serine-rich coiled-coil 1 -2.49465
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.01015