| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cobalt sulfate heptahydrate 100.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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68 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDOC | aldolase C, fructose-bisphosphate | 6.68925 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 5.3659 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 4.82985 |
| MAMLD1 | mastermind-like domain containing 1 | 4.77405 |
| GATA2 | GATA binding protein 2 | 4.2647 |
| HBB | hemoglobin, beta | 3.61137 |
| MMP1 | matrix metallopeptidase 1 | 3.51013 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.3303 |
| HBA1 | hemoglobin, alpha 1 | 3.30633 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.80515 |
| TBC1D31 | TBC1 domain family, member 31 | 2.76175 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 2.70385 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.5284 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 2.5241 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.3484 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 2.33755 |
| CPA4 | carboxypeptidase A4 | 2.31355 |
| DENND2D | DENN/MADD domain containing 2D | 2.2868 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 2.2483 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.20255 |
| WFDC1 | WAP four-disulfide core domain 1 | 2.1822 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.1546 |
| LGMN | legumain | 2.147 |
| CHN1 | chimerin 1 | 2.11425 |
| CSAG2 | CSAG family, member 2 | 2.09045 |
| SSUH2 | ssu-2 homolog (C. elegans) | 2.07955 |
| LOC112694756 | uncharaterized LOC112694756 | 2.07675 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2.0734 |
| BRD9 | bromodomain containing 9 | 2.06595 |
| IL5 | interleukin 5 | 2.0586 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 2.05635 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.0546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRAPPC3 | trafficking protein particle complex 3 | -5.40128 |
| COG2 | component of oligomeric golgi complex 2 | -5.2646 |
| KIF14 | kinesin family member 14 | -5.14685 |
| LDHD | lactate dehydrogenase D | -4.3381 |
| ANKRD10 | ankyrin repeat domain 10 | -3.52105 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -3.31567 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.23438 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -3.10775 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -3.03375 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.96455 |
| ACSF2 | acyl-CoA synthetase family member 2 | -2.80975 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.7697 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.7064 |
| CD320 | CD320 molecule | -2.7056 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase | -2.63925 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.59355 |
| HOXA7 | homeobox A7 | -2.5722 |
| COG5 | component of oligomeric golgi complex 5 | -2.53377 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.493 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.35905 |
| SRPK2 | SRSF protein kinase 2 | -2.35658 |
| FBXO3 | F-box protein 3 | -2.31245 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.28775 |
| BAX | BCL2-associated X protein | -2.23285 |
| DEXI | Dexi homolog (mouse) | -2.226 |
| CBR3 | carbonyl reductase 3 | -2.22505 |
| COPS6 | COP9 signalosome subunit 6 | -2.20123 |
| C1S | complement component 1, s subcomponent | -2.1697 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -2.1508 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -2.11545 |
| TOR1A | torsin family 1, member A (torsin A) | -2.10938 |
| RINT1 | RAD50 interactor 1 | -2.10775 |
| RPIA | ribose 5-phosphate isomerase A | -2.0979 |
| LIG4 | ligase IV, DNA, ATP-dependent | -2.0736 |
| MRPS33 | mitochondrial ribosomal protein S33 | -2.0706 |
| SLC35F6 | solute carrier family 35, member F6 | -2.0106 |