CRCGN015_MCF10A.TP53.M_24H:N18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-epoxybutane 10.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.1051
STK10 serine/threonine kinase 10 4.4089
MOK MOK protein kinase 3.86515
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.8175
APOE apolipoprotein E 3.76483
AGR2 anterior gradient 2 3.361
MMP1 matrix metallopeptidase 1 3.1181
TBC1D31 TBC1 domain family, member 31 2.95095
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.6663
CENPE centromere protein E, 312kDa 2.4897
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.28275
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.2764
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.26955
GSTZ1 glutathione S-transferase zeta 1 2.16335
SRD5A3 steroid 5 alpha-reductase 3 2.14605
APOC1 apolipoprotein C-I 2.01655

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -5.8215
ACOT9 acyl-CoA thioesterase 9 -5.5037
HMG20B high mobility group 20B -4.99318
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.22895
HSPA1A heat shock 70kDa protein 1A -3.60135
ACAA1 acetyl-CoA acyltransferase 1 -3.0442
CREB1 cAMP responsive element binding protein 1 -2.65356
PRDX4 peroxiredoxin 4 -2.29365
DUSP14 dual specificity phosphatase 14 -2.2642
APOO apolipoprotein O -2.1989
PCCB propionyl CoA carboxylase, beta polypeptide -2.11875
VAT1 vesicle amine transport 1 -2.1031