| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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91 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | 5.41715 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 5.1694 |
| IDE | insulin-degrading enzyme | 4.75193 |
| ABHD4 | abhydrolase domain containing 4 | 4.66275 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.4795 |
| STK10 | serine/threonine kinase 10 | 4.08568 |
| TBX2 | T-box 2 | 3.98222 |
| TSPAN6 | tetraspanin 6 | 3.90863 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.4357 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.35115 |
| ZNF134 | zinc finger protein 134 | 3.34955 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.9063 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 2.8785 |
| ZNF419 | zinc finger protein 419 | 2.84695 |
| CADM1 | cell adhesion molecule 1 | 2.82205 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.80535 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.80525 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 2.6402 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 2.57413 |
| HHEX | hematopoietically expressed homeobox | 2.4413 |
| ZNF304 | zinc finger protein 304 | 2.4187 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 2.39205 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 2.35548 |
| ZNF222 | zinc finger protein 222 | 2.34215 |
| BAX | BCL2-associated X protein | 2.31948 |
| NOSIP | nitric oxide synthase interacting protein | 2.31225 |
| CERK | ceramide kinase | 2.3017 |
| TMEM204 | transmembrane protein 204 | 2.27655 |
| KIF11 | kinesin family member 11 | 2.1869 |
| BCL3 | B-cell CLL/lymphoma 3 | 2.18055 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.1802 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 2.17885 |
| FOXF1 | forkhead box F1 | 2.1718 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 2.16365 |
| ZNF211 | zinc finger protein 211 | 2.14965 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 2.13545 |
| HYOU1 | hypoxia up-regulated 1 | 2.12335 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 2.1214 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 2.12 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 2.10255 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | 2.08225 |
| SMYD5 | SMYD family member 5 | 2.0756 |
| SPARCL1 | SPARC-like 1 (hevin) | 2.0642 |
| HBB | hemoglobin, beta | 2.05175 |
| SMAD3 | SMAD family member 3 | 2.04453 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 | 2.03365 |
| EXOSC5 | exosome component 5 | 2.0149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -5.97275 |
| CYCS | cytochrome c, somatic | -5.26915 |
| CDC45 | cell division cycle 45 | -4.76095 |
| TCTA | T-cell leukemia translocation altered | -4.40565 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -4.32485 |
| BLCAP | bladder cancer associated protein | -3.90015 |
| RPS5 | ribosomal protein S5 | -3.65815 |
| CD81 | CD81 molecule | -3.49875 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.03083 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.74072 |
| ZMYM2 | zinc finger, MYM-type 2 | -2.45483 |
| GRN | granulin | -2.41602 |
| RPL34 | ribosomal protein L34 | -2.37155 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -2.36005 |
| COX5A | cytochrome c oxidase subunit Va | -2.29905 |
| CTSL | cathepsin L | -2.25725 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -2.2039 |
| LACTB2 | lactamase, beta 2 | -2.1972 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -2.1957 |
| ANXA5 | annexin A5 | -2.1879 |
| RPL39 | ribosomal protein L39 | -2.18645 |
| RPS19 | ribosomal protein S19 | -2.1753 |
| RLIM | ring finger protein, LIM domain interacting | -2.138 |
| INTS3 | integrator complex subunit 3 | -2.13775 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | -2.13615 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -2.12365 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -2.1201 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | -2.10175 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.0871 |
| SKIC2 | SKI2 subunit of superkiller complex | -2.0835 |
| SH2D1A | SH2 domain containing 1A | -2.08064 |
| TDG | thymine-DNA glycosylase | -2.07605 |
| BCL10 | B-cell CLL/lymphoma 10 | -2.0707 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 | -2.0666 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -2.0631 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -2.06255 |
| PHKB | phosphorylase kinase, beta | -2.05205 |
| CKAP5 | cytoskeleton associated protein 5 | -2.04255 |
| GARS1 | glycyl-tRNA synthetase 1 | -2.03875 |
| RPS11 | ribosomal protein S11 | -2.03185 |
| APOD | apolipoprotein D | -2.01365 |
| HSPB2 | heat shock 27kDa protein 2 | -2.0136 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | -2.0117 |
| RPL36AL | ribosomal protein L36a-like | -2.01085 |
