CRCGN015_MCF10A.TP53.M_24H:N24 Gene Set
Genes
56 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
5.5992
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
5.06885
|
|
LGMN
|
legumain
|
4.6115
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
3.16975
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.87765
|
|
COL4A5
|
collagen, type IV, alpha 5
|
2.81475
|
|
CCNF
|
cyclin F
|
2.78467
|
|
STEAP4
|
STEAP family member 4
|
2.5476
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.5464
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
2.48145
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.4355
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
2.2054
|
|
ITPR1
|
inositol 1,4,5-trisphosphate receptor, type 1
|
2.1681
|
|
ZNF23
|
zinc finger protein 23
|
2.16115
|
|
SSBP3
|
single stranded DNA binding protein 3
|
2.143
|
|
SGMS1
|
sphingomyelin synthase 1
|
2.13225
|
|
FAM193B
|
family with sequence similarity 193, member B
|
2.12655
|
|
PRR15L
|
proline rich 15-like
|
2.11695
|
|
P4HA1
|
prolyl 4-hydroxylase, alpha polypeptide I
|
2.1135
|
|
CSAD
|
cysteine sulfinic acid decarboxylase
|
2.05275
|
|
NVL
|
nuclear VCP-like
|
2.04645
|
|
SLC44A4
|
solute carrier family 44, member 4
|
2.0435
|
|
HOXB13
|
homeobox B13
|
2.0348
|
|
PSPH
|
phosphoserine phosphatase
|
2.02863
|
|
WLS
|
wntless Wnt ligand secretion mediator
|
2.0267
|
|
ENOPH1
|
enolase-phosphatase 1
|
2.0132
|
|
ZNF780A
|
zinc finger protein 780A
|
2.0036
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-5.77015
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-5.25325
|
|
CCNB1
|
cyclin B1
|
-4.9681
|
|
LYPLA1
|
lysophospholipase I
|
-4.80473
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.5812
|
|
CD320
|
CD320 molecule
|
-4.4683
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.2836
|
|
RPS5
|
ribosomal protein S5
|
-4.2813
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.8598
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-3.26852
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.22662
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-2.9173
|
|
ERVMER34-1
|
endogenous retrovirus group MER34, member 1
|
-2.83595
|
|
NUP155
|
nucleoporin 155kDa
|
-2.81025
|
|
WDR70
|
WD repeat domain 70
|
-2.69535
|
|
RAMP3
|
receptor (G protein-coupled) activity modifying protein 3
|
-2.60685
|
|
S1PR1
|
sphingosine-1-phosphate receptor 1
|
-2.56505
|
|
VWF
|
von Willebrand factor
|
-2.49805
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-2.47895
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.3441
|
|
CBR3
|
carbonyl reductase 3
|
-2.30605
|
|
KCTD11
|
potassium channel tetramerization domain containing 11
|
-2.2078
|
|
SQLE
|
squalene epoxidase
|
-2.1506
|
|
LHX6
|
LIM homeobox 6
|
-2.1115
|
|
LOC114841035
|
uncharacterized LOC114841035
|
-2.07735
|
|
SART1
|
squamous cell carcinoma antigen recognized by T cells
|
-2.06675
|
|
PAIP1
|
poly(A) binding protein interacting protein 1
|
-2.05162
|
|
TMEM222
|
transmembrane protein 222
|
-2.02462
|
|
LYPLA1-TCEA1
|
LYPLA1-TCEA1 readthrough
|
-2.00605
|
