CRCGN015_MCF10A.TP53.M_24H:O02 Gene Set
Genes
36 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
4.3652
|
|
RPL39L
|
ribosomal protein L39-like
|
3.74381
|
|
CREB1
|
cAMP responsive element binding protein 1
|
3.55971
|
|
EAPP
|
E2F-associated phosphoprotein
|
3.44074
|
|
SPAG4
|
sperm associated antigen 4
|
3.43902
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
3.27273
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
3.05063
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.41343
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.39656
|
|
ACLY
|
ATP citrate lyase
|
2.38494
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.35504
|
|
SRP14
|
signal recognition particle 14kDa (homologous Alu RNA binding protein)
|
2.31208
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.31146
|
|
HDAC7
|
histone deacetylase 7
|
2.3054
|
|
CSNK1A1
|
casein kinase 1, alpha 1
|
2.26953
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
2.06568
|
|
EVL
|
Enah/Vasp-like
|
2.05888
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
2.04664
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-7.02351
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.16241
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.77852
|
|
GRN
|
granulin
|
-4.01655
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-3.84699
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.82874
|
|
HMG20B
|
high mobility group 20B
|
-3.82816
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-3.37074
|
|
KRT14
|
keratin 14, type I
|
-2.91905
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.62748
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.59961
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.47324
|
|
ZFYVE16
|
zinc finger, FYVE domain containing 16
|
-2.33678
|
|
STXBP2
|
syntaxin binding protein 2
|
-2.29157
|
|
GGT5
|
gamma-glutamyltransferase 5
|
-2.11853
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.06294
|
|
RABGGTA
|
Rab geranylgeranyltransferase, alpha subunit
|
-2.01814
|
|
ATP13A2
|
ATPase type 13A2
|
-2.0168
|
