CRCGN015_MCF10A.TP53.M_24H:O03 Gene Set
Genes
42 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
4.5149
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.87704
|
|
E2F2
|
E2F transcription factor 2
|
3.80913
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
3.76612
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
3.30059
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
3.11888
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
3.11691
|
|
LGMN
|
legumain
|
2.96396
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.65594
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.55429
|
|
SNX11
|
sorting nexin 11
|
2.51387
|
|
EPHA3
|
EPH receptor A3
|
2.42602
|
|
C5
|
complement component 5
|
2.37522
|
|
AGR2
|
anterior gradient 2
|
2.29202
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.25389
|
|
GABRA1
|
gamma-aminobutyric acid (GABA) A receptor, alpha 1
|
2.22863
|
|
AMACR
|
alpha-methylacyl-CoA racemase
|
2.19561
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.18962
|
|
LOC102724652
|
alpha-crystallin A chain
|
2.1798
|
|
CA14
|
carbonic anhydrase XIV
|
2.13177
|
|
LIPF
|
lipase, gastric
|
2.12151
|
|
HBB
|
hemoglobin, beta
|
2.0904
|
|
ACTL6B
|
actin-like 6B
|
2.08735
|
|
FBXO5
|
F-box protein 5
|
2.06814
|
|
SV2B
|
synaptic vesicle glycoprotein 2B
|
2.0555
|
|
TRMT9B
|
tRNA methyltransferase 9B (putative)
|
2.05519
|
|
PRDM13
|
PR domain containing 13
|
2.04171
|
|
NEUROD6
|
neuronal differentiation 6
|
2.04169
|
|
CA5A
|
carbonic anhydrase VA, mitochondrial
|
2.04143
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-4.93381
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.3065
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.93649
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.76545
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-3.42288
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
-3.22656
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.11849
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-2.87574
|
|
NUP85
|
nucleoporin 85kDa
|
-2.43346
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.28612
|
|
TMEM94
|
transmembrane protein 94
|
-2.15154
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
-2.13502
|
|
CASKIN2
|
CASK interacting protein 2
|
-2.08618
|
