CRCGN015_MCF10A.TP53.M_24H:O05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 4.48447
SNX11 sorting nexin 11 3.75658
MAP7 microtubule-associated protein 7 3.26347
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.64841
SNAP25 synaptosomal-associated protein, 25kDa 2.54228
MAMLD1 mastermind-like domain containing 1 2.51124
GATA3 GATA binding protein 3 2.44479
TXNL4B thioredoxin-like 4B 2.42919
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.20655
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.19833
PDLIM1 PDZ and LIM domain 1 2.19645
LRRC59 leucine rich repeat containing 59 2.15418
RBKS ribokinase 2.12732
ALDOC aldolase C, fructose-bisphosphate 2.12257
STMN2 stathmin 2 2.08264

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.43085
VAT1 vesicle amine transport 1 -3.41011
FOS FBJ murine osteosarcoma viral oncogene homolog -3.3633
COG7 component of oligomeric golgi complex 7 -3.31871
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.24381
DERA deoxyribose-phosphate aldolase (putative) -3.15749
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.82673
HMG20B high mobility group 20B -2.74405
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.68252
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.62435
GRWD1 glutamate-rich WD repeat containing 1 -2.58383
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.43897
DIPK1A divergent protein kinase domain 1A -2.26408
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.18225