| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | indometacin 33.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 5.38542 |
| RNF167 | ring finger protein 167 | 5.3447 |
| HMOX1 | heme oxygenase 1 | 4.9852 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.7048 |
| ABHD4 | abhydrolase domain containing 4 | 4.4548 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 4.17325 |
| NRBF2 | nuclear receptor binding factor 2 | 4.0097 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.76017 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.7507 |
| PRKCH | protein kinase C, eta | 3.63028 |
| COMP | cartilage oligomeric matrix protein | 3.6021 |
| CHEK1 | checkpoint kinase 1 | 3.59578 |
| WIF1 | WNT inhibitory factor 1 | 3.5845 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.45865 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 2.96128 |
| NVL | nuclear VCP-like | 2.70365 |
| USP6NL | USP6 N-terminal like | 2.57245 |
| DENND2D | DENN/MADD domain containing 2D | 2.5308 |
| PDLIM1 | PDZ and LIM domain 1 | 2.52775 |
| UMOD | uromodulin | 2.5222 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 2.3843 |
| EGF | epidermal growth factor | 2.36305 |
| RASAL2 | RAS protein activator like 2 | 2.34175 |
| SCAP | SREBF chaperone | 2.2535 |
| TLR2 | toll-like receptor 2 | 2.1904 |
| ECM1 | extracellular matrix protein 1 | 2.15895 |
| THBS3 | thrombospondin 3 | 2.14905 |
| MUS81 | MUS81 structure-specific endonuclease subunit | 2.0506 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 2.0354 |
| SCAMP4 | secretory carrier membrane protein 4 | 2.0342 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 | 2.03183 |
| SPATA7 | spermatogenesis associated 7 | 2.0198 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 2.0144 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.0058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -5.2087 |
| SLC35F2 | solute carrier family 35, member F2 | -4.845 |
| DSG2 | desmoglein 2 | -4.84385 |
| HSPA8 | heat shock 70kDa protein 8 | -4.60688 |
| THAP11 | THAP domain containing 11 | -2.70285 |
| XK | X-linked Kx blood group | -2.61225 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.60302 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -2.51875 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -2.49175 |
| SMAP1 | small ArfGAP 1 | -2.4081 |
| RMDN1 | regulator of microtubule dynamics 1 | -2.3746 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -2.3689 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.32555 |
| CD320 | CD320 molecule | -2.32215 |
| PRAMEF26 | PRAME family member 26 | -2.28495 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -2.2793 |
| DEK | DEK proto-oncogene | -2.19085 |
| MAGEA10 | melanoma antigen family A10 | -2.16955 |
| COX6C | cytochrome c oxidase subunit VIc | -2.16555 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -2.16123 |
| CNTNAP1 | contactin associated protein 1 | -2.14325 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -2.12682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -2.08385 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -2.05785 |
| RNF11 | ring finger protein 11 | -2.05015 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.0436 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -2.0378 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -2.03545 |
| PDCD10 | programmed cell death 10 | -2.02 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -2.00735 |
| VMP1 | vacuole membrane protein 1 | -2.00285 |
