| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | indometacin 11.07 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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43 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 4.9652 |
| SPAG4 | sperm associated antigen 4 | 4.8117 |
| BMP4 | bone morphogenetic protein 4 | 4.25455 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.9017 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.8721 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.4422 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.26955 |
| CORO1A | coronin, actin binding protein, 1A | 2.8105 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.7826 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.7047 |
| CD53 | CD53 molecule | 2.6988 |
| SNX7 | sorting nexin 7 | 2.62035 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.5968 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.55275 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.459 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.39275 |
| TGFB3 | transforming growth factor, beta 3 | 2.384 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.3072 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 2.26615 |
| PLA2G15 | phospholipase A2, group XV | 2.24935 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 2.1696 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 2.10155 |
| CDK5 | cyclin-dependent kinase 5 | 2.06105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -4.77602 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.70665 |
| HSPA1A | heat shock 70kDa protein 1A | -3.01535 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.0133 |
| TSPAN3 | tetraspanin 3 | -2.91598 |
| CBR3 | carbonyl reductase 3 | -2.8975 |
| CDK2 | cyclin-dependent kinase 2 | -2.4148 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.30895 |
| STXBP3 | syntaxin binding protein 3 | -2.30465 |
| NCK2 | NCK adaptor protein 2 | -2.22215 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -2.19275 |
| THAP11 | THAP domain containing 11 | -2.1748 |
| RBBP7 | retinoblastoma binding protein 7 | -2.14135 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.12 |
| APOO | apolipoprotein O | -2.111 |
| ANXA5 | annexin A5 | -2.0919 |
| MTMR6 | myotubularin related protein 6 | -2.08 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -2.072 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -2.07065 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.04705 |
