CRCGN015_MCF10A.TP53.M_24H:O15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 10.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

69 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5D lysine (K)-specific demethylase 5D 4.70045
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.6768
CNRIP1 cannabinoid receptor interacting protein 1 4.483
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 4.0056
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.79572
ADRB2 adrenoceptor beta 2, surface 3.589
WIF1 WNT inhibitory factor 1 3.58585
ACAA1 acetyl-CoA acyltransferase 1 3.38897
TBPL1 TBP-like 1 3.16995
USP9Y ubiquitin specific peptidase 9, Y-linked 3.0065
PDLIM1 PDZ and LIM domain 1 2.97155
HBA1 hemoglobin, alpha 1 2.82378
ZFY zinc finger protein, Y-linked 2.7531
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.7472
LGMN legumain 2.74265
BAAT bile acid CoA:amino acid N-acyltransferase 2.6504
DENND2D DENN/MADD domain containing 2D 2.5123
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.50355
CRELD2 cysteine-rich with EGF-like domains 2 2.4725
NCK1 NCK adaptor protein 1 2.40348
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.3913
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.33497
MT1G metallothionein 1G 2.29595
TIMP3 TIMP metallopeptidase inhibitor 3 2.28004
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.213
BAG1 BCL2-associated athanogene 2.17655
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.16695
GPN3 GPN-loop GTPase 3 2.1573
MT1E metallothionein 1E 2.14565
QDPR quinoid dihydropteridine reductase 2.113
CADM1 cell adhesion molecule 1 2.09775
MT1H metallothionein 1H 2.06312
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 2.038
GPR171 G protein-coupled receptor 171 2.0192

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -5.25012
SLC35F2 solute carrier family 35, member F2 -4.80295
C2CD5 C2 calcium-dependent domain containing 5 -4.71975
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.61365
NUP85 nucleoporin 85kDa -4.54135
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.3851
CLTB clathrin, light chain B -3.82732
MRPS7 mitochondrial ribosomal protein S7 -3.2485
MRPL58 mitochondrial ribosomal protein L58 -3.18565
UBA1 ubiquitin-like modifier activating enzyme 1 -3.15805
PUDP pseudouridine 5'-phosphatase -3.0747
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.90135
KDM5C lysine (K)-specific demethylase 5C -2.8821
ATP11B ATPase, class VI, type 11B -2.8813
GRB2 growth factor receptor-bound protein 2 -2.8443
KCTD2 potassium channel tetramerization domain containing 2 -2.6759
SMC1A structural maintenance of chromosomes 1A -2.58885
SUMO4 small ubiquitin-like modifier 4 -2.52885
KDM6A lysine (K)-specific demethylase 6A -2.46198
TSPAN3 tetraspanin 3 -2.45505
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.40602
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.3191
TMEM94 transmembrane protein 94 -2.29055
NT5DC2 5'-nucleotidase domain containing 2 -2.19705
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.16255
CDR2L cerebellar degeneration-related protein 2-like -2.1014
GTF2IRD1 GTF2I repeat domain containing 1 -2.0919
JPT1 Jupiter microtubule associated homolog 1 -2.08285
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.06095
CASKIN2 CASK interacting protein 2 -2.0436
KEAP1 kelch-like ECH-associated protein 1 -2.0419
VIL1 villin 1 -2.03515
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.01935
GRM4 glutamate receptor, metabotropic 4 -2.01145
TLK2 tousled-like kinase 2 -2.00873