| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | catechol 10.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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69 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM5D | lysine (K)-specific demethylase 5D | 4.70045 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.6768 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.483 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 4.0056 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.79572 |
| ADRB2 | adrenoceptor beta 2, surface | 3.589 |
| WIF1 | WNT inhibitory factor 1 | 3.58585 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.38897 |
| TBPL1 | TBP-like 1 | 3.16995 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 3.0065 |
| PDLIM1 | PDZ and LIM domain 1 | 2.97155 |
| HBA1 | hemoglobin, alpha 1 | 2.82378 |
| ZFY | zinc finger protein, Y-linked | 2.7531 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.7472 |
| LGMN | legumain | 2.74265 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | 2.6504 |
| DENND2D | DENN/MADD domain containing 2D | 2.5123 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.50355 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.4725 |
| NCK1 | NCK adaptor protein 1 | 2.40348 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.3913 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.33497 |
| MT1G | metallothionein 1G | 2.29595 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 2.28004 |
| RIPPLY2-CYB5R4 | RIPPLY2-CYB5R4 readthrough | 2.213 |
| BAG1 | BCL2-associated athanogene | 2.17655 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 2.16695 |
| GPN3 | GPN-loop GTPase 3 | 2.1573 |
| MT1E | metallothionein 1E | 2.14565 |
| QDPR | quinoid dihydropteridine reductase | 2.113 |
| CADM1 | cell adhesion molecule 1 | 2.09775 |
| MT1H | metallothionein 1H | 2.06312 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 2.038 |
| GPR171 | G protein-coupled receptor 171 | 2.0192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | -5.25012 |
| SLC35F2 | solute carrier family 35, member F2 | -4.80295 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.71975 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.61365 |
| NUP85 | nucleoporin 85kDa | -4.54135 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.3851 |
| CLTB | clathrin, light chain B | -3.82732 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.2485 |
| MRPL58 | mitochondrial ribosomal protein L58 | -3.18565 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -3.15805 |
| PUDP | pseudouridine 5'-phosphatase | -3.0747 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.90135 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.8821 |
| ATP11B | ATPase, class VI, type 11B | -2.8813 |
| GRB2 | growth factor receptor-bound protein 2 | -2.8443 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.6759 |
| SMC1A | structural maintenance of chromosomes 1A | -2.58885 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.52885 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.46198 |
| TSPAN3 | tetraspanin 3 | -2.45505 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.40602 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.3191 |
| TMEM94 | transmembrane protein 94 | -2.29055 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.19705 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -2.16255 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.1014 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -2.0919 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.08285 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.06095 |
| CASKIN2 | CASK interacting protein 2 | -2.0436 |
| KEAP1 | kelch-like ECH-associated protein 1 | -2.0419 |
| VIL1 | villin 1 | -2.03515 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -2.01935 |
| GRM4 | glutamate receptor, metabotropic 4 | -2.01145 |
| TLK2 | tousled-like kinase 2 | -2.00873 |