| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfallate 100.72 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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82 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 5.15602 |
| CDCA4 | cell division cycle associated 4 | 5.1213 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.72985 |
| TBX2 | T-box 2 | 4.44803 |
| UGDH | UDP-glucose 6-dehydrogenase | 4.33595 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.38695 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 2.59425 |
| WDR41 | WD repeat domain 41 | 2.56965 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 2.5639 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 2.52495 |
| SREK1IP1 | SREK1-interacting protein 1 | 2.4387 |
| C4BPB | complement component 4 binding protein, beta | 2.4057 |
| MRPL17 | mitochondrial ribosomal protein L17 | 2.40495 |
| MBNL1 | muscleblind-like splicing regulator 1 | 2.32694 |
| TUBA3C | tubulin, alpha 3c | 2.30605 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | 2.284 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.22825 |
| DCPH1 | damage control phosphatase 1 | 2.2137 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 2.2022 |
| CREB1 | cAMP responsive element binding protein 1 | 2.18699 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 2.176 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.17205 |
| VAMP8 | vesicle-associated membrane protein 8 | 2.1714 |
| SERPINA4 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | 2.167 |
| LGMN | legumain | 2.158 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H | 2.1556 |
| MRPL9 | mitochondrial ribosomal protein L9 | 2.13928 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 2.1173 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.1117 |
| NISCH | nischarin | 2.0992 |
| STAC | SH3 and cysteine rich domain | 2.0987 |
| PEF1 | penta-EF-hand domain containing 1 | 2.07125 |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia | 2.0665 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 2.06075 |
| TBXT | T-box transcription factor T | 2.0326 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 2.0303 |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 | 2.02255 |
| CCNDBP1 | cyclin D-type binding-protein 1 | 2.0118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.553 |
| PUF60 | poly-U binding splicing factor 60KDa | -5.4501 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -5.1568 |
| TSPAN4 | tetraspanin 4 | -5.05185 |
| MSMO1 | methylsterol monooxygenase 1 | -5.0 |
| ADI1 | acireductone dioxygenase 1 | -4.47915 |
| UBE3C | ubiquitin protein ligase E3C | -4.4196 |
| EXOSC4 | exosome component 4 | -3.4376 |
| RPS5 | ribosomal protein S5 | -3.03185 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.99165 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -2.98265 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.95965 |
| COX6C | cytochrome c oxidase subunit VIc | -2.8956 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | -2.8784 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.80581 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -2.56505 |
| BMAL1 | basic helix-loop-helix ARNT like 1 | -2.55118 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.4819 |
| SCRIB | scribbled planar cell polarity protein | -2.47715 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.45498 |
| TMEM267 | transmembrane protein 267 | -2.44505 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -2.44478 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.402 |
| ZMPSTE24 | zinc metallopeptidase STE24 | -2.40085 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.39845 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -2.36355 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -2.32665 |
| IRX4 | iroquois homeobox 4 | -2.3136 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -2.30415 |
| BACE1 | beta-site APP-cleaving enzyme 1 | -2.29985 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -2.29705 |
| LPIN1 | lipin 1 | -2.28245 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.23225 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | -2.22655 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -2.2218 |
| WDR70 | WD repeat domain 70 | -2.19725 |
| COG5 | component of oligomeric golgi complex 5 | -2.18395 |
| WRN | Werner syndrome, RecQ helicase-like | -2.17485 |
| IPO13 | importin 13 | -2.1316 |
| SEM1 | SEM1 26S proteasome subunit | -2.0992 |
| RNF144A | ring finger protein 144A | -2.0676 |
| DHCR7 | 7-dehydrocholesterol reductase | -2.03323 |
| INTS8 | integrator complex subunit 8 | -2.0299 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -2.01128 |