CRCGN015_MCF10A.TP53.M_24H:O23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 35.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

684 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 6.44205
PPP1R13B protein phosphatase 1, regulatory subunit 13B 5.0316
TOPBP1 topoisomerase (DNA) II binding protein 1 4.90945
UGDH UDP-glucose 6-dehydrogenase 4.6027
TRAPPC6A trafficking protein particle complex 6A 4.27215
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.109
TENT4A terminal nucleotidyltransferase 4A 4.0338
CARMIL1 capping protein regulator and myosin 1 linker 1 3.71965
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.69885
RAB21 RAB21, member RAS oncogene family 3.69475
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.57635
ZBTB35 zinc finger and BTB domain containing 35 3.5031
GRB7 growth factor receptor-bound protein 7 3.48665
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.4305
R3HCC1L R3H domain and coiled-coil containing 1-like 3.40985
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 3.35445
ARL4C ADP-ribosylation factor-like 4C 3.35282
PTK2B protein tyrosine kinase 2 beta 3.33672
FOS FBJ murine osteosarcoma viral oncogene homolog 3.24625
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 3.2325
HYOU1 hypoxia up-regulated 1 3.1968
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.0899
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.0789
DIPK1A divergent protein kinase domain 1A 3.07795
ACTL8 actin-like 8 3.05825
SYNDIG1 synapse differentiation inducing 1 3.03185
E4F1 E4F transcription factor 1 3.0137
ZNF79 zinc finger protein 79 3.0041
SCAI suppressor of cancer cell invasion 2.9622
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.9509
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.946
IPO13 importin 13 2.94015
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.9225
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.919
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.916
ELAC1 elaC ribonuclease Z 1 2.9128
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.87915
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.8762
CIAO3 cytosolic iron-sulfur assembly component 3 2.8597
DGKQ diacylglycerol kinase, theta 110kDa 2.82815
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.8224
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.81495
SCN2A sodium channel, voltage gated, type II alpha subunit 2.8074
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.80527
GSDMB gasdermin B 2.80165
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.79395
GPR85 G protein-coupled receptor 85 2.7932
NCS1 neuronal calcium sensor 1 2.77245
UNC13A unc-13 homolog A (C. elegans) 2.76515
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.7623
KANSL3 KAT8 regulatory NSL complex subunit 3 2.7585
KITLG KIT ligand 2.73975
COL6A1 collagen, type VI, alpha 1 2.734
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.6799
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.67898
EGF epidermal growth factor 2.67765
ANKRD40CL ANKRD40 C-terminal like 2.67155
CNOT3 CCR4-NOT transcription complex, subunit 3 2.6649
CA4 carbonic anhydrase IV 2.66175
ICAM5 intercellular adhesion molecule 5, telencephalin 2.65825
AURKB aurora kinase B 2.65765
CA7 carbonic anhydrase VII 2.65015
GOLT1B golgi transport 1B 2.6463
SPRED2 sprouty-related, EVH1 domain containing 2 2.6383
KMT2D lysine (K)-specific methyltransferase 2D 2.6379
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine 2.63605
PYY peptide YY 2.6358
IREB2 iron-responsive element binding protein 2 2.6268
TFDP3 transcription factor Dp family, member 3 2.6261
MOB3B MOB kinase activator 3B 2.619
COL19A1 collagen, type XIX, alpha 1 2.61095
GSE1 Gse1 coiled-coil protein 2.60965
PTMS parathymosin 2.60885
ETV3 ets variant 3 2.604
ADGRB2 adhesion G protein-coupled receptor B2 2.60245
GRK5 G protein-coupled receptor kinase 5 2.602
BAX BCL2-associated X protein 2.5975
FOXH1 forkhead box H1 2.5871
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.5862
IMPG2 interphotoreceptor matrix proteoglycan 2 2.58075
SYN3 synapsin III 2.57795
ZNF804A zinc finger protein 804A 2.57545
ZNF132 zinc finger protein 132 2.57415
DSCC1 DNA replication and sister chromatid cohesion 1 2.57315
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.56562
UVRAG UV radiation resistance associated 2.56075
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 2.5597
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.5591
THUMPD2 THUMP domain containing 2 2.55895
TEDC2 tubulin epsilon and delta complex 2 2.5536
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 2.552
ANKRD49 ankyrin repeat domain 49 2.54965
PKDREJ polycystin (PKD) family receptor for egg jelly 2.54035
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.53725
KIAA1549L KIAA1549-like 2.53555
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.53032
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.5269
TEX13A testis expressed 13A 2.522
PLAAT2 phospholipase A and acyltransferase 2 2.5216
NOL10 nucleolar protein 10 2.52115
DAND5 DAN domain family member 5, BMP antagonist 2.5208
AKAP5 A kinase (PRKA) anchor protein 5 2.51995
MMP2 matrix metallopeptidase 2 2.518
TUBAL3 tubulin, alpha-like 3 2.5109
ZFP2 ZFP2 zinc finger protein 2.50765
PARM1 prostate androgen-regulated mucin-like protein 1 2.50555
ZNF415 zinc finger protein 415 2.50265
THBS3 thrombospondin 3 2.5024
TRIM13 tripartite motif containing 13 2.5021
IFT140 intraflagellar transport 140 2.5004
SLC38A2 solute carrier family 38, member 2 2.4974
ARL15 ADP-ribosylation factor-like 15 2.49565
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.49245
WDR91 WD repeat domain 91 2.4898
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.488
MAPK10 mitogen-activated protein kinase 10 2.4835
USP27X ubiquitin specific peptidase 27, X-linked 2.48135
SH3GL3 SH3-domain GRB2-like 3 2.48065
PKP2 plakophilin 2 2.4737
PEX13 peroxisomal biogenesis factor 13 2.4726
CTSD cathepsin D 2.47175
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.4675
GPR22 G protein-coupled receptor 22 2.46715
CADM1 cell adhesion molecule 1 2.46597
CAMK4 calcium/calmodulin-dependent protein kinase IV 2.4658
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.46145
GHR growth hormone receptor 2.4613
TKFC triokinase/FMN cyclase 2.4611
TERT telomerase reverse transcriptase 2.45915
ZNF480 zinc finger protein 480 2.4516
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.44935
STRN striatin, calmodulin binding protein 2.44637
POLM polymerase (DNA directed), mu 2.4422
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 2.4422
HTRA1 HtrA serine peptidase 1 2.44045
ATG10 autophagy related 10 2.4401
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2.43785
PEX5 peroxisomal biogenesis factor 5 2.4356
DYNC2I1 dynein 2 intermediate chain 1 2.43495
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.43455
MRPS11 mitochondrial ribosomal protein S11 2.43073
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.4298
ZNF550 zinc finger protein 550 2.42775
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.42645
EMX1 empty spiracles homeobox 1 2.42525
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 2.423
LUM lumican 2.4217
TFRC transferrin receptor 2.42115
LOC102724652 alpha-crystallin A chain 2.4197
TCF21 transcription factor 21 2.4194
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.4178
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.4157
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.4154
ZBTB44 zinc finger and BTB domain containing 44 2.4119
CHURC1-FNTB CHURC1-FNTB readthrough 2.41105
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 2.4051
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.4026
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.40225
NTF3 neurotrophin 3 2.3998
TLN2 talin 2 2.39873
ANKRD6 ankyrin repeat domain 6 2.39283
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.39005
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.38745
ZNF8 zinc finger protein 8 2.3847
LYRM1 LYR motif containing 1 2.3845
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.38375
ZNF273 zinc finger protein 273 2.3834
FEZF2 FEZ family zinc finger 2 2.382
TAS2R3 taste receptor, type 2, member 3 2.3799
SOCS4 suppressor of cytokine signaling 4 2.3769
MYL9 myosin, light chain 9, regulatory 2.3746
MTERF4 mitochondrial transcription termination factor 4 2.37315
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.37295
RLBP1 retinaldehyde binding protein 1 2.3706
UMOD uromodulin 2.37055
CD200R1 CD200 receptor 1 2.37035
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.36985
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.36965
TMEM259 transmembrane protein 259 2.36705
SNX13 sorting nexin 13 2.36002
CCDC177 coiled-coil domain containing 177 2.3553
BICDL1 BICD family like cargo adaptor 1 2.355
ZNF154 zinc finger protein 154 2.35285
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 2.35225
CLDN14 claudin 14 2.35215
KLHL1 kelch-like family member 1 2.35105
LIN7B lin-7 homolog B (C. elegans) 2.3485
MRLN myoregulin 2.34815
PDYN prodynorphin 2.3478
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 2.34155
NEMP1 nuclear envelope integral membrane protein 1 2.3397
STARD5 StAR-related lipid transfer (START) domain containing 5 2.33815
FGFR4 fibroblast growth factor receptor 4 2.33725
PRICKLE3 prickle homolog 3 (Drosophila) 2.33685
MARK2 MAP/microtubule affinity-regulating kinase 2 2.33668
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 2.33413
MCPH1 microcephalin 1 2.33255
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.32667
CCRL2 chemokine (C-C motif) receptor-like 2 2.32545
MGAM2 maltase-glucoamylase 2 (putative) 2.32435
CRX cone-rod homeobox 2.3237
SSTR4 somatostatin receptor 4 2.3206
IGFBP5 insulin-like growth factor binding protein 5 2.32003
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.31942
DOC2B double C2-like domains, beta 2.3194
NEUROD1 neuronal differentiation 1 2.318
PYDC1 PYD (pyrin domain) containing 1 2.31735
ZNF780A zinc finger protein 780A 2.31665
NEK11 NIMA-related kinase 11 2.3154
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.31495
ZFYVE26 zinc finger, FYVE domain containing 26 2.31462
VPS26C VPS26 endosomal protein sorting factor C 2.31407
SOX2 SRY (sex determining region Y)-box 2 2.31365
PTPRU protein tyrosine phosphatase, receptor type, U 2.3126
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.3084
FGF23 fibroblast growth factor 23 2.30445
AK8 adenylate kinase 8 2.30355
NOTCH1 notch 1 2.2993
MC3R melanocortin 3 receptor 2.2979
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.29635
MOCS1 molybdenum cofactor synthesis 1 2.2955
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.29443
IL7 interleukin 7 2.2944
THAP9 THAP domain containing 9 2.2936
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.2933
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 2.29235
BET1L Bet1 golgi vesicular membrane trafficking protein-like 2.29155
ADORA2A adenosine A2a receptor 2.2906
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 2.2906
GPATCH2L G patch domain containing 2-like 2.29015
SPRYD7 SPRY domain containing 7 2.2899
SSTR2 somatostatin receptor 2 2.2858
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.28373
FRMPD4 FERM and PDZ domain containing 4 2.28255
ZNF208 zinc finger protein 208 2.2778
CDK3 cyclin-dependent kinase 3 2.27735
ZNF350 zinc finger protein 350 2.27525
DOC2A double C2-like domains, alpha 2.27505
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.2698
ZBTB48 zinc finger and BTB domain containing 48 2.2688
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.26585
H2BC6 H2B clustered histone 6 2.26415
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.26255
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.2625
TBC1D22B TBC1 domain family, member 22B 2.26135
DGKB diacylglycerol kinase, beta 90kDa 2.2611
MOBP myelin-associated oligodendrocyte basic protein 2.25973
TXNL4B thioredoxin-like 4B 2.2579
LBX1 ladybird homeobox 1 2.25495
UTF1 undifferentiated embryonic cell transcription factor 1 2.2518
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.2505
H2BC12 H2B clustered histone 12 2.24923
PEG10 paternally expressed 10 2.24795
ENTREP2 endosomal transmembrane epsin interactor 2 2.2468
KCTD20 potassium channel tetramerization domain containing 20 2.2461
PLPPR1 phospholipid phosphatase related 1 2.24525
MEST mesoderm specific transcript 2.24275
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.24205
BMP10 bone morphogenetic protein 10 2.2413
ARHGAP32 Rho GTPase activating protein 32 2.2403
LARP7 La ribonucleoprotein domain family, member 7 2.2402
MMP13 matrix metallopeptidase 13 2.23975
ZFPM2 zinc finger protein, FOG family member 2 2.2381
CATSPERG catsper channel auxiliary subunit gamma 2.23765
PRKG1 protein kinase, cGMP-dependent, type I 2.236
FCHO1 FCH domain only 1 2.2352
PPP1R2C PPP1R2C family member C 2.2345
LINS1 lines homolog 1 2.2342
ZNF665 zinc finger protein 665 2.23405
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.2328
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.23235
FN3K fructosamine 3 kinase 2.232
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 2.2317
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.23115
RASA3 RAS p21 protein activator 3 2.22818
FFAR3 free fatty acid receptor 3 2.228
JADE3 jade family PHD finger 3 2.22745
DDN dendrin 2.22325
RPUSD2 RNA pseudouridylate synthase domain containing 2 2.22225
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.21985
ZG16 zymogen granule protein 16 2.21845
ATRNL1 attractin-like 1 2.21843
EPHA3 EPH receptor A3 2.2184
LOXL1 lysyl oxidase-like 1 2.2169
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.216
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.2158
IL13RA1 interleukin 13 receptor, alpha 1 2.21526
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.2145
BRWD1 bromodomain and WD repeat domain containing 1 2.21303
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like 2.2122
BCO1 beta-carotene oxygenase 1 2.2109
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.21065
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.2101
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.2096
ZNF155 zinc finger protein 155 2.2081
HRK harakiri, BCL2 interacting protein 2.20732
TRHDE thyrotropin-releasing hormone degrading enzyme 2.2073
KIAA0408 KIAA0408 2.207
EVI2A ecotropic viral integration site 2A 2.2064
ZNF257 zinc finger protein 257 2.20595
TMEM39A transmembrane protein 39A 2.2059
NFYB nuclear transcription factor Y, beta 2.2056
ARHGAP22 Rho GTPase activating protein 22 2.201
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.199
PRAMEF26 PRAME family member 26 2.19885
RNF17 ring finger protein 17 2.1935
ZNF343 zinc finger protein 343 2.19325
ACE angiotensin I converting enzyme 2.1916
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.19145
UTS2 urotensin 2 2.191
CLIC2 chloride intracellular channel 2 2.1902
GRTP1 growth hormone regulated TBC protein 1 2.1894
DENND4A DENN/MADD domain containing 4A 2.18895
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.1887
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.1859
THRB thyroid hormone receptor, beta 2.1859
ZNF682 zinc finger protein 682 2.18565
TEX10 testis expressed 10 2.1856
ZMYM6 zinc finger, MYM-type 6 2.18545
GCG glucagon 2.1842
LUZP4 leucine zipper protein 4 2.18045
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.18025
HBE1 hemoglobin, epsilon 1 2.17625
ARMCX4 armadillo repeat containing, X-linked 4 2.17615
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.17537
OR2C1 olfactory receptor, family 2, subfamily C, member 1 2.1734
DCAF4 DDB1 and CUL4 associated factor 4 2.1727
PRODH proline dehydrogenase (oxidase) 1 2.1718
ANO2 anoctamin 2, calcium activated chloride channel 2.1706
SHOX short stature homeobox 2.17005
LPXN leupaxin 2.16855
NOX3 NADPH oxidase 3 2.1672
GJA9 gap junction protein, alpha 9, 59kDa 2.1656
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.16535
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.16515
MYO1A myosin IA 2.1651
SPIN2A spindlin family, member 2A 2.165
KATNBL1 katanin p80 subunit B-like 1 2.16475
OVOL1 ovo-like zinc finger 1 2.163
MTAP methylthioadenosine phosphorylase 2.16262
ANAPC2 anaphase promoting complex subunit 2 2.16245
GSTCD glutathione S-transferase, C-terminal domain containing 2.1624
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.15815
GRM3 glutamate receptor, metabotropic 3 2.1574
NR5A2 nuclear receptor subfamily 5, group A, member 2 2.15598
TRIM46 tripartite motif containing 46 2.1532
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.152
BLNK B-cell linker 2.1518
KCNK13 potassium channel, two pore domain subfamily K, member 13 2.1514
TSPAN2 tetraspanin 2 2.1504
PACC1 proton activated chloride channel 1 2.1503
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 2.14715
IL1R1 interleukin 1 receptor, type I 2.14707
GRM7 glutamate receptor, metabotropic 7 2.14705
PCDHGA3 protocadherin gamma subfamily A, 3 2.14575
ZC3H3 zinc finger CCCH-type containing 3 2.1456
RTN2 reticulon 2 2.14515
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.142
PRDM9 PR domain containing 9 2.14115
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.14103
LGALS12 lectin, galactoside-binding, soluble, 12 2.1383
MSH2 mutS homolog 2 2.1377
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.13545
TOP3B topoisomerase (DNA) III beta 2.13525
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.13475
LRRTM4 leucine rich repeat transmembrane neuronal 4 2.13405
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.1323
KRT83 keratin 83, type II 2.13215
EMC10 ER membrane protein complex subunit 10 2.13125
ZNF253 zinc finger protein 253 2.1271
CD1B CD1b molecule 2.1262
KLHL12 kelch-like family member 12 2.12495
SOCS2 suppressor of cytokine signaling 2 2.12425
ZNF221 zinc finger protein 221 2.12415
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.1238
EDN2 endothelin 2 2.1231
BRSK2 BR serine/threonine kinase 2 2.11955
INSL5 insulin-like 5 2.1195
ACVRL1 activin A receptor type II-like 1 2.11885
ZNF839 zinc finger protein 839 2.1171
GUCA2A guanylate cyclase activator 2A (guanylin) 2.1155
GSTM2 glutathione S-transferase mu 2 (muscle) 2.1155
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 2.1154
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 2.11532
CLDN8 claudin 8 2.1148
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.11285
KALRN kalirin, RhoGEF kinase 2.1125
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.112
RBMXL2 RNA binding motif protein, X-linked-like 2 2.1115
NPAP1 nuclear pore associated protein 1 2.1111
CLCA4 chloride channel accessory 4 2.1089
WDR25 WD repeat domain 25 2.1085
TMEM70 transmembrane protein 70 2.10672
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.10632
MTNR1A melatonin receptor 1A 2.10595
PRLR prolactin receptor 2.10551
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.10493
ZNF254 zinc finger protein 254 2.104
ZNF235 zinc finger protein 235 2.10352
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.10287
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.10085
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.09845
TCP10L t-complex 10-like 2.0981
OTOR otoraplin 2.098
MMP23B matrix metallopeptidase 23B 2.09775
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.09608
CLEC4M C-type lectin domain family 4, member M 2.09185
ZBTB3 zinc finger and BTB domain containing 3 2.0918
CERS4 ceramide synthase 4 2.0918
JUN jun proto-oncogene 2.0917
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.0896
STIMATE STIM activating enhancer 2.0886
LRRK1 leucine-rich repeat kinase 1 2.0881
GRK4 G protein-coupled receptor kinase 4 2.08588
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.0856
TPD52-MRPS28 TPD52-MRPS28 readthrough 2.08438
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.0838
ADRA1B adrenoceptor alpha 1B 2.0815
NCF2 neutrophil cytosolic factor 2 2.08135
FOXF2 forkhead box F2 2.0812
CLCNKB chloride channel, voltage-sensitive Kb 2.081
HES2 hes family bHLH transcription factor 2 2.08075
SUGCT succinyl-CoA:glutarate-CoA transferase 2.0796
ZNF180 zinc finger protein 180 2.0792
TAS2R10 taste receptor, type 2, member 10 2.07825
TMEM19 transmembrane protein 19 2.0781
PITPNM3 PITPNM family member 3 2.0778
AP1AR adaptor-related protein complex 1 associated regulatory protein 2.07585
TP53I11 tumor protein p53 inducible protein 11 2.07562
SNAI1 snail family zinc finger 1 2.0736
AGRP agouti related neuropeptide 2.0734
THPO thrombopoietin 2.07272
PYCR3 pyrroline-5-carboxylate reductase 3 2.06935
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.06895
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.06895
HACD3 3-hydroxyacyl-CoA dehydratase 3 2.06835
PCDHGA10 protocadherin gamma subfamily A, 10 2.0668
CDC73 cell division cycle 73 2.06675
PDE12 phosphodiesterase 12 2.065
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.06405
H4C7 H4 clustered histone 7 2.06375
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 2.0635
TIMP2 TIMP metallopeptidase inhibitor 2 2.06305
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.06255
INSRR insulin receptor-related receptor 2.0613
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.06125
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 2.0612
TOM1L2 target of myb1-like 2 (chicken) 2.06105
H2AP H2A.P histone 2.06055
RAD51AP1 RAD51 associated protein 1 2.06025
GADD45A growth arrest and DNA-damage-inducible, alpha 2.06025
MAGEB4 melanoma antigen family B4 2.0602
ARHGAP35 Rho GTPase activating protein 35 2.06008
BCAM basal cell adhesion molecule (Lutheran blood group) 2.05993
SAMD4B sterile alpha motif domain containing 4B 2.0592
SIRT4 sirtuin 4 2.05915
DOT1L DOT1-like histone H3K79 methyltransferase 2.0587
PLPPR4 phospholipid phosphatase related 4 2.0586
HOXD12 homeobox D12 2.0585
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.0582
SLCO5A1 solute carrier organic anion transporter family, member 5A1 2.0575
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 2.0572
GOLGA6B golgin A6 family, member B 2.0568
DAO D-amino-acid oxidase 2.0567
TDRD12 tudor domain containing 12 2.05605
RFPL3 ret finger protein-like 3 2.0558
DUSP21 dual specificity phosphatase 21 2.05565
DENND1B DENN/MADD domain containing 1B 2.055
EXO5 exonuclease 5 2.0548
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.05335
PRDM5 PR domain containing 5 2.05255
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.0525
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.0499
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.04985
PSG4 pregnancy specific beta-1-glycoprotein 4 2.04955
SPACA1 sperm acrosome associated 1 2.04905
CDON cell adhesion associated, oncogene regulated 2.0486
REG3A regenerating islet-derived 3 alpha 2.0485
VTCN1 V-set domain containing T cell activation inhibitor 1 2.04795
ZNF322 zinc finger protein 322 2.04785
FRMD1 FERM domain containing 1 2.0474
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.04705
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 2.047
GPR68 G protein-coupled receptor 68 2.0468
TREM2 triggering receptor expressed on myeloid cells 2 2.04555
PPP1R37 protein phosphatase 1, regulatory subunit 37 2.04137
STXBP5L syntaxin binding protein 5-like 2.0411
APOB apolipoprotein B 2.0406
NRL neural retina leucine zipper 2.04045
ARHGAP8 Rho GTPase activating protein 8 2.03977
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.03934
IL25 interleukin 25 2.0393
KLK15 kallikrein-related peptidase 15 2.0389
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.03702
SSBP3 single stranded DNA binding protein 3 2.03555
LINC02854 long intergenic non-protein coding RNA 2854 2.0349
HPGDS hematopoietic prostaglandin D synthase 2.0345
ASS1 argininosuccinate synthase 1 2.0344
MAU2 MAU2 sister chromatid cohesion factor 2.03423
JCAD junctional cadherin 5 associated 2.03385
FAM135A family with sequence similarity 135, member A 2.03345
VGLL1 vestigial-like family member 1 2.03313
IFT54 intraflagellar transport 54 2.033
ZNF814 zinc finger protein 814 2.03285
LRRC19 leucine rich repeat containing 19 2.0321
EVL Enah/Vasp-like 2.0319
C8G complement component 8, gamma polypeptide 2.03165
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 2.03165
SH2D3C SH2 domain containing 3C 2.03145
KPNA5 karyopherin alpha 5 (importin alpha 6) 2.03135
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.03125
OPN1MW3 opsin 1, medium wave sensitive 3 2.02995
ZNF232 zinc finger protein 232 2.02985
ZNF669 zinc finger protein 669 2.02965
GJA5 gap junction protein, alpha 5, 40kDa 2.02925
FST follistatin 2.02898
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.02758
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.0274
FAM13C family with sequence similarity 13, member C 2.0273
NPVF neuropeptide VF precursor 2.02725
PRCC papillary renal cell carcinoma (translocation-associated) 2.0269
COPZ2 coatomer protein complex, subunit zeta 2 2.02675
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.0265
SYT13 synaptotagmin XIII 2.0261
PCDHGA11 protocadherin gamma subfamily A, 11 2.02555
PDE7B phosphodiesterase 7B 2.02545
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.02485
CALCRL calcitonin receptor-like 2.02353
CDH9 cadherin 9, type 2 (T1-cadherin) 2.0233
SYNPO synaptopodin 2.0231
E2F8 E2F transcription factor 8 2.02305
GREM1 gremlin 1, DAN family BMP antagonist 2.02277
AJAP1 adherens junctions associated protein 1 2.02274
ZNF37A zinc finger protein 37A 2.02085
PAK1IP1 PAK1 interacting protein 1 2.0208
MAB21L2 mab-21-like 2 (C. elegans) 2.02008
VENTX VENT homeobox 2.01925
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.019
PURG purine-rich element binding protein G 2.01895
ZNF701 zinc finger protein 701 2.01612
CRLF2 cytokine receptor-like factor 2 2.01605
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 2.01585
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.01557
FPR3 formyl peptide receptor 3 2.0141
EML4 echinoderm microtubule associated protein like 4 2.014
MRPS18C mitochondrial ribosomal protein S18C 2.0138
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.0135
ADAM22 ADAM metallopeptidase domain 22 2.01142
TBC1D15 TBC1 domain family, member 15 2.00955
ZNF225 zinc finger protein 225 2.00865
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 2.00805
TRIM10 tripartite motif containing 10 2.00798
POU6F2 POU class 6 homeobox 2 2.0079
PMFBP1 polyamine modulated factor 1 binding protein 1 2.0076
LOC102723996 ICOS ligand 2.00749
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 2.0071
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.00685
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.00677
POLRMT polymerase (RNA) mitochondrial (DNA directed) 2.0061
FSCN2 fascin actin-bundling protein 2, retinal 2.00595
NXPH3 neurexophilin 3 2.00575
CASS4 Cas scaffolding protein family member 4 2.0055
OMP olfactory marker protein 2.0032
GPR32 G protein-coupled receptor 32 2.00305
TULP2 tubby like protein 2 2.00275
DENND5B DENN/MADD domain containing 5B 2.00255
TEX15 testis expressed 15 2.0024
PRMT8 protein arginine methyltransferase 8 2.00225
BTK Bruton agammaglobulinemia tyrosine kinase 2.0016

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -5.9127
VDAC1 voltage-dependent anion channel 1 -5.10575
PCCB propionyl CoA carboxylase, beta polypeptide -4.84305
CD81 CD81 molecule -4.7445
BASP1 brain abundant, membrane attached signal protein 1 -4.0915
CBR3 carbonyl reductase 3 -3.9861
TES testin LIM domain protein -3.98113
COTL1 coactosin-like F-actin binding protein 1 -3.8994
PUF60 poly-U binding splicing factor 60KDa -3.8853
GRWD1 glutamate-rich WD repeat containing 1 -3.71195
TSPAN3 tetraspanin 3 -3.68595
CD320 CD320 molecule -3.63925
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -3.5287
CSK c-src tyrosine kinase -3.47035
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -3.46245
MRPS2 mitochondrial ribosomal protein S2 -3.45805
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.32315
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.22815
BLCAP bladder cancer associated protein -3.1134
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.0557
OXCT1 3-oxoacid CoA transferase 1 -3.0303
PSRC1 proline/serine-rich coiled-coil 1 -3.02615
TUBA4A tubulin, alpha 4a -3.01645
TM9SF3 transmembrane 9 superfamily member 3 -3.01315
SKIC2 SKI2 subunit of superkiller complex -2.99695
CRTAP cartilage associated protein -2.9562
CTSL cathepsin L -2.9108
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -2.88665
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -2.8773
LRP10 low density lipoprotein receptor-related protein 10 -2.8603
TSKU tsukushi, small leucine rich proteoglycan -2.74535
TERF2IP telomeric repeat binding factor 2, interacting protein -2.74105
CLTC clathrin, heavy chain (Hc) -2.7185
UBE3C ubiquitin protein ligase E3C -2.71375
LAGE3 L antigen family, member 3 -2.705
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.68775
FBXO7 F-box protein 7 -2.67765
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.66365
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.6289
NT5DC2 5'-nucleotidase domain containing 2 -2.62575
SLC35B1 solute carrier family 35, member B1 -2.6067
DYNLRB1 dynein, light chain, roadblock-type 1 -2.6062
SLIT2 slit homolog 2 (Drosophila) -2.5887
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.58815
ARHGAP19 Rho GTPase activating protein 19 -2.58423
FOSL1 FOS-like antigen 1 -2.57525
MAPK13 mitogen-activated protein kinase 13 -2.56008
CST3 cystatin C -2.5544
FASTKD5 FAST kinase domains 5 -2.53415
SUN2 Sad1 and UNC84 domain containing 2 -2.4976
ZNF185 zinc finger protein 185 (LIM domain) -2.4317
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.4259
PFN1 profilin 1 -2.4254
CDC25B cell division cycle 25B -2.4135
LMTK1 lemur tail kinase 1 -2.41235
CALCB calcitonin-related polypeptide beta -2.41185
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.3602
FAM50A family with sequence similarity 50, member A -2.35585
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.35462
HSPA1A heat shock 70kDa protein 1A -2.35455
ANO10 anoctamin 10 -2.34875
COG4 component of oligomeric golgi complex 4 -2.3483
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.34525
BAG3 BCL2-associated athanogene 3 -2.3385
GMPPA GDP-mannose pyrophosphorylase A -2.3309
NUP43 nucleoporin 43kDa -2.32745
DENR density-regulated protein -2.3259
GRIA2 glutamate receptor, ionotropic, AMPA 2 -2.3182
EIF6 eukaryotic translation initiation factor 6 -2.31795
GLB1 galactosidase, beta 1 -2.30035
PYCR1 pyrroline-5-carboxylate reductase 1 -2.2978
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.29755
AOAH acyloxyacyl hydrolase (neutrophil) -2.2889
MGST2 microsomal glutathione S-transferase 2 -2.28395
TSC22D4 TSC22 domain family, member 4 -2.2829
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.2727
XPO6 exportin 6 -2.26965
PYGL phosphorylase, glycogen, liver -2.2687
ADGRE5 adhesion G protein-coupled receptor E5 -2.2674
ILK integrin-linked kinase -2.2665
TOP2B topoisomerase (DNA) II beta 180kDa -2.2643
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.26095
PUM1 pumilio RNA-binding family member 1 -2.25965
SACS sacsin molecular chaperone -2.2581
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.25595
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.2397
PGM1 phosphoglucomutase 1 -2.22845
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -2.21655
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.2018
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.1996
EGR3 early growth response 3 -2.19395
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -2.18045
S100A11 S100 calcium binding protein A11 -2.17875
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -2.1784
RPN1 ribophorin I -2.17765
KEAP1 kelch-like ECH-associated protein 1 -2.17715
PNKP polynucleotide kinase 3'-phosphatase -2.1659
CAB39 calcium binding protein 39 -2.15715
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.1547
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.108
SARAF store-operated calcium entry-associated regulatory factor -2.1061
CUEDC2 CUE domain containing 2 -2.08195
EPS8 epidermal growth factor receptor pathway substrate 8 -2.0751
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.07005
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.0672
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.0604
ECI2 enoyl-CoA delta isomerase 2 -2.0594
KDM1A lysine (K)-specific demethylase 1A -2.0503
FPGS folylpolyglutamate synthase -2.0357
OXA1L oxidase (cytochrome c) assembly 1-like -2.02445
DUSP4 dual specificity phosphatase 4 -2.02358
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -2.0213
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.01485
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.01345
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.0129