| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-aminodiphenyl 100.07 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COMP | cartilage oligomeric matrix protein | 4.37915 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 4.3383 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 4.31965 |
| NUCB2 | nucleobindin 2 | 4.2813 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 4.12763 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.56435 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.47148 |
| GATA3 | GATA binding protein 3 | 3.36022 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 3.2548 |
| GLRX | glutaredoxin (thioltransferase) | 3.13775 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 3.11133 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.02195 |
| INPP5J | inositol polyphosphate-5-phosphatase J | 2.6921 |
| OPRPN | opiorphin prepropeptide | 2.65575 |
| S100A4 | S100 calcium binding protein A4 | 2.3274 |
| FAM234B | family with sequence similarity 234 member B | 2.28375 |
| HYOU1 | hypoxia up-regulated 1 | 2.2736 |
| NOSIP | nitric oxide synthase interacting protein | 2.27115 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 2.21585 |
| SIX6 | SIX homeobox 6 | 2.20685 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.2031 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.1602 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 2.08255 |
| TNN | tenascin N | 2.08235 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 2.06005 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.04315 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 2.0393 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.03355 |
| OLAH | oleoyl-ACP hydrolase | 2.02215 |
| COL4A5 | collagen, type IV, alpha 5 | 2.01135 |
| IFRD1 | interferon-related developmental regulator 1 | 2.00787 |
| SMR3A | submaxillary gland androgen regulated protein 3A | 2.00755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRWD1 | glutamate-rich WD repeat containing 1 | -5.24565 |
| COG2 | component of oligomeric golgi complex 2 | -5.0741 |
| CD81 | CD81 molecule | -4.7132 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.63705 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -4.24657 |
| TCEA2 | transcription elongation factor A (SII), 2 | -3.53305 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -3.3056 |
| HOXA5 | homeobox A5 | -3.1552 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -2.84405 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | -2.8236 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -2.8118 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.74202 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -2.68975 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | -2.63755 |
| SNX6 | sorting nexin 6 | -2.59055 |
| CBR3 | carbonyl reductase 3 | -2.4551 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.42415 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.41615 |
| EDNRB | endothelin receptor type B | -2.3954 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.3803 |
| HSPB2 | heat shock 27kDa protein 2 | -2.33855 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | -2.3352 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -2.33403 |
| STAC | SH3 and cysteine rich domain | -2.29005 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.2432 |
| NUP93 | nucleoporin 93kDa | -2.1936 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | -2.1872 |
| TRAPPC2L | trafficking protein particle complex 2-like | -2.18515 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -2.1155 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -2.0634 |
| GPM6B | glycoprotein M6B | -2.04335 |
