| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-aminodiphenyl 33.36 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WFS1 | Wolfram syndrome 1 (wolframin) | 5.12375 |
| MYLK | myosin light chain kinase | 4.87925 |
| MEF2C | myocyte enhancer factor 2C | 4.66383 |
| KLHL21 | kelch-like family member 21 | 4.4321 |
| AGR2 | anterior gradient 2 | 4.3083 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 3.47975 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.22215 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 3.20417 |
| WIF1 | WNT inhibitory factor 1 | 3.11625 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 3.09049 |
| DENND2D | DENN/MADD domain containing 2D | 2.9807 |
| OXSR1 | oxidative stress responsive 1 | 2.9607 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.73785 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 2.66255 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 | 2.5992 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.53035 |
| MAPK9 | mitogen-activated protein kinase 9 | 2.4875 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 | 2.4513 |
| GPC3 | glypican 3 | 2.3528 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 2.31505 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.2943 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.23965 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.2023 |
| INSIG1 | insulin induced gene 1 | 2.13872 |
| SOD3 | superoxide dismutase 3, extracellular | 2.09865 |
| ACBD3 | acyl-CoA binding domain containing 3 | 2.0661 |
| PEG3 | paternally expressed 3 | 2.0395 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.03667 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 2.02595 |
| CDCA3 | cell division cycle associated 3 | 2.02535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -6.0015 |
| PCNA | proliferating cell nuclear antigen | -5.0 |
| PUF60 | poly-U binding splicing factor 60KDa | -5.0 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.38275 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.95115 |
| STXBP2 | syntaxin binding protein 2 | -3.932 |
| HOXA5 | homeobox A5 | -3.8478 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -3.58033 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -2.62555 |
| ANXA2 | annexin A2 | -2.62465 |
| PLCB4 | phospholipase C, beta 4 | -2.58623 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase | -2.5314 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -2.41205 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | -2.36665 |
| PANK2 | pantothenate kinase 2 | -2.29835 |
| ACE2 | angiotensin I converting enzyme 2 | -2.27352 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -2.236 |
| RPS5 | ribosomal protein S5 | -2.18965 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -2.17987 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.17165 |
| BIN3 | bridging integrator 3 | -2.14825 |
| NOP53 | NOP53 ribosome biogenesis factor | -2.1118 |
| METTL18 | methyltransferase like 18 | -2.1003 |
| UBOX5 | U-box domain containing 5 | -2.06955 |
| CBR3 | carbonyl reductase 3 | -2.06505 |
| ZNF133 | zinc finger protein 133 | -2.059 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.0527 |
| ZNF329 | zinc finger protein 329 | -2.03625 |
