| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-aminodiphenyl 11.12 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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94 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG4 | sperm associated antigen 4 | 5.514 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.2255 |
| MEF2C | myocyte enhancer factor 2C | 5.19805 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.99172 |
| TBX2 | T-box 2 | 4.89785 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.1154 |
| LGMN | legumain | 3.85055 |
| TCTN1 | tectonic family member 1 | 3.6237 |
| CDK19 | cyclin-dependent kinase 19 | 3.19123 |
| GPATCH8 | G patch domain containing 8 | 2.94875 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 2.69425 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.57905 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 2.5317 |
| AGR2 | anterior gradient 2 | 2.47675 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | 2.4684 |
| ITGA7 | integrin, alpha 7 | 2.39595 |
| CENPE | centromere protein E, 312kDa | 2.3364 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 2.3314 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 2.31315 |
| MSRA | methionine sulfoxide reductase A | 2.30725 |
| UBAP1 | ubiquitin associated protein 1 | 2.28437 |
| KAT7 | K(lysine) acetyltransferase 7 | 2.2829 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 2.26465 |
| RUFY1 | RUN and FYVE domain containing 1 | 2.2526 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 2.2184 |
| DCTN4 | dynactin 4 (p62) | 2.20135 |
| DCLRE1B | DNA cross-link repair 1B | 2.1397 |
| RBL1 | retinoblastoma-like 1 | 2.13515 |
| SAR1B | secretion associated, Ras related GTPase 1B | 2.12275 |
| TNNC2 | troponin C type 2 (fast) | 2.11205 |
| EFNB2 | ephrin-B2 | 2.10843 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 2.07735 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 2.06805 |
| TMOD1 | tropomodulin 1 | 2.0651 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.06215 |
| LAPTM5 | lysosomal protein transmembrane 5 | 2.05975 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 2.05522 |
| OLFML2B | olfactomedin-like 2B | 2.05365 |
| CSNK1A1 | casein kinase 1, alpha 1 | 2.05354 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 2.0511 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 2.04165 |
| MYF6 | myogenic factor 6 (herculin) | 2.04145 |
| COMMD3 | COMM domain containing 3 | 2.0296 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 2.0218 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 | 2.02097 |
| CASQ2 | calsequestrin 2 (cardiac muscle) | 2.015 |
| EMP3 | epithelial membrane protein 3 | 2.0011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MPC2 | mitochondrial pyruvate carrier 2 | -5.036 |
| CDC20 | cell division cycle 20 | -5.0 |
| HSPA8 | heat shock 70kDa protein 8 | -4.91285 |
| GNAS | GNAS complex locus | -3.64321 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.471 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -3.00525 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.9702 |
| CD96 | CD96 molecule | -2.7658 |
| STAT4 | signal transducer and activator of transcription 4 | -2.7593 |
| PIH1D1 | PIH1 domain containing 1 | -2.7154 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.6969 |
| ELOVL1 | ELOVL fatty acid elongase 1 | -2.52322 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.45487 |
| HEG1 | heart development protein with EGF-like domains 1 | -2.43878 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.4346 |
| IFITM3 | interferon induced transmembrane protein 3 | -2.43335 |
| MVP | major vault protein | -2.4279 |
| PFN1 | profilin 1 | -2.31805 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | -2.29565 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.2924 |
| SRBD1 | S1 RNA binding domain 1 | -2.28025 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -2.27065 |
| DDX19B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B | -2.22635 |
| MNX1 | motor neuron and pancreas homeobox 1 | -2.222 |
| WNT11 | wingless-type MMTV integration site family, member 11 | -2.18505 |
| MADD | MAP-kinase activating death domain | -2.18475 |
| UBE3C | ubiquitin protein ligase E3C | -2.18235 |
| TUBA4A | tubulin, alpha 4a | -2.16915 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -2.15845 |
| PXDC1 | PX domain containing 1 | -2.14665 |
| VGLL3 | vestigial-like family member 3 | -2.14505 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -2.13438 |
| MYRIP | myosin VIIA and Rab interacting protein | -2.12675 |
| PAX6 | paired box 6 | -2.1237 |
| SKAP1 | src kinase associated phosphoprotein 1 | -2.12175 |
| ATP9A | ATPase, class II, type 9A | -2.1171 |
| MED17 | mediator complex subunit 17 | -2.10495 |
| MTIF2 | mitochondrial translational initiation factor 2 | -2.08635 |
| ZFHX4 | zinc finger homeobox 4 | -2.0816 |
| SCG3 | secretogranin III | -2.0793 |
| THBS2 | thrombospondin 2 | -2.07435 |
| PRR5 | proline rich 5 (renal) | -2.06122 |
| INS | insulin | -2.04945 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.0475 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -2.0442 |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | -2.01815 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | -2.00705 |
