CRCGN015_MCF10A.TP53.M_24H:P18 Gene Set
Genes
49 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.2926
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
5.1542
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
5.08725
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
4.94885
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.92385
|
|
KIF5C
|
kinesin family member 5C
|
4.21753
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
3.397
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.21187
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
2.96905
|
|
CCNF
|
cyclin F
|
2.80152
|
|
NDUFS4
|
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
|
2.78735
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.67635
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.54005
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.32312
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
2.31165
|
|
TLCD3A
|
TLC domain containing 3A
|
2.26265
|
|
CRLF3
|
cytokine receptor-like factor 3
|
2.1356
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
2.13085
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
2.1153
|
|
TEX30
|
testis expressed 30
|
2.04795
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
2.02395
|
|
NOP2
|
NOP2 nucleolar protein
|
2.01955
|
|
RNPS1
|
RNA binding protein S1, serine-rich domain
|
2.0182
|
|
EVL
|
Enah/Vasp-like
|
2.01595
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-5.6331
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.3278
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-4.90045
|
|
HMG20B
|
high mobility group 20B
|
-4.56357
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.2468
|
|
STXBP2
|
syntaxin binding protein 2
|
-3.536
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-3.00515
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.92999
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.89195
|
|
SERPINA1
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
|
-2.46803
|
|
TKTL1
|
transketolase-like 1
|
-2.40298
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.3987
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.2921
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.2833
|
|
TKT
|
transketolase
|
-2.2656
|
|
SLC47A1
|
solute carrier family 47 (multidrug and toxin extrusion), member 1
|
-2.2089
|
|
HTRA1
|
HtrA serine peptidase 1
|
-2.1832
|
|
PIH1D1
|
PIH1 domain containing 1
|
-2.1657
|
|
PODXL2
|
podocalyxin-like 2
|
-2.13945
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.11115
|
|
SLC12A1
|
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
|
-2.1091
|
|
BHMT
|
betaine--homocysteine S-methyltransferase
|
-2.08965
|
|
ARL2
|
ADP-ribosylation factor-like 2
|
-2.0827
|
|
DYSF
|
dysferlin
|
-2.0819
|
|
EHHADH
|
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
|
-2.06815
|
