CRCGN015_MCF10A.TP53.M_24H:P22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenzo[a,h]pyrene 100.48 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.316
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 5.21755
CXCR4 chemokine (C-X-C motif) receptor 4 5.09298
KIF5C kinesin family member 5C 4.89388
SQOR sulfide quinone oxidoreductase 4.6501
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.26442
SNX11 sorting nexin 11 4.07998
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.7463
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 3.2104
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.2035
CGRRF1 cell growth regulator with ring finger domain 1 2.97595
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.80355
CDK7 cyclin-dependent kinase 7 2.6494
DENND2D DENN/MADD domain containing 2D 2.4634
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.2631
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.24705
PRAMEF26 PRAME family member 26 2.2255
EAPP E2F-associated phosphoprotein 2.22195
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.1804
CBX1 chromobox homolog 1 2.14495
LSM1 LSM1, U6 small nuclear RNA associated 2.1396
LRRC61 leucine rich repeat containing 61 2.0936
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.0835
PRKG2 protein kinase, cGMP-dependent, type II 2.07995
EPHA1 EPH receptor A1 2.0393
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.0283
DENND1C DENN/MADD domain containing 1C 2.02205
CD3D CD3d molecule, delta (CD3-TCR complex) 2.01595
KIF5A kinesin family member 5A 2.01305
SCN5A sodium channel, voltage gated, type V alpha subunit 2.0047
ALLC allantoicase 2.00275

decreased expression

Symbol Name Standardized Value
CDC45 cell division cycle 45 -5.55075
HMG20B high mobility group 20B -5.0426
TCTA T-cell leukemia translocation altered -3.494
ANKRD10 ankyrin repeat domain 10 -3.4373
BASP1 brain abundant, membrane attached signal protein 1 -3.2798
TRAP1 TNF receptor-associated protein 1 -3.039
GRWD1 glutamate-rich WD repeat containing 1 -2.9341
RPS5 ribosomal protein S5 -2.7925
KDM3A lysine (K)-specific demethylase 3A -2.7642
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.52435
TXLNA taxilin alpha -2.4347
BLCAP bladder cancer associated protein -2.41015
CD81 CD81 molecule -2.2941
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.203
COTL1 coactosin-like F-actin binding protein 1 -2.132
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.12005
CYTH2 cytohesin 2 -2.0748
PRPF38B pre-mRNA processing factor 38B -2.06772
TAC4 tachykinin 4 (hemokinin) -2.04795
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -2.04105