CRCGN015_MCF10A.WT.HP_24H:A04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

84 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LAGE3 L antigen family, member 3 5.2335
WIF1 WNT inhibitory factor 1 4.73431
FAIM Fas apoptotic inhibitory molecule 3.96907
NMT1 N-myristoyltransferase 1 3.55888
PLSCR3 phospholipid scramblase 3 3.24134
MMP11 matrix metallopeptidase 11 2.76058
KREMEN2 kringle containing transmembrane protein 2 2.66491
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.54045
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.53601
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.44135
CEP70 centrosomal protein 70kDa 2.41348
DNM1 dynamin 1 2.40827
SLC10A3 solute carrier family 10, member 3 2.40697
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.37726
MKS1 Meckel syndrome, type 1 2.37026
IP6K1 inositol hexakisphosphate kinase 1 2.30146
PTPRF protein tyrosine phosphatase, receptor type, F 2.2606
MOSPD3 motile sperm domain containing 3 2.22471
HIRA histone cell cycle regulator 2.21272
ARID5B AT rich interactive domain 5B (MRF1-like) 2.19815
RTL8A retrotransposon Gag like 8A 2.1678
JRK Jrk homolog (mouse) 2.15516
ALX3 ALX homeobox 3 2.15143
SLC12A9 solute carrier family 12, member 9 2.14752
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.13761
AEBP1 AE binding protein 1 2.12965
PTK7 protein tyrosine kinase 7 (inactive) 2.11269
CYB5R3 cytochrome b5 reductase 3 2.10109
CUTA cutA divalent cation tolerance homolog (E. coli) 2.09772
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 2.09472
FKBPL FK506 binding protein like 2.08744
ANGPTL8 angiopoietin like 8 2.07926
MUC1 mucin 1, cell surface associated 2.07618
SNAP29 synaptosomal-associated protein, 29kDa 2.05771
MBNL1 muscleblind-like splicing regulator 1 2.05577
SDC3 syndecan 3 2.04365
CEP131 centrosomal protein 131kDa 2.0286
CHD8 chromodomain helicase DNA binding protein 8 2.02014
CTRB2 chymotrypsinogen B2 2.01447
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.00893
ZW10 zw10 kinetochore protein 2.00883
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.00866
SMIM40 small integral membrane protein 40 2.00846

decreased expression

Symbol Name Standardized Value
UBE3C ubiquitin protein ligase E3C -8.95234
PCCB propionyl CoA carboxylase, beta polypeptide -5.60543
PGAM4 phosphoglycerate mutase family member 4 -4.83304
CDC25B cell division cycle 25B -4.56359
HMG20B high mobility group 20B -4.17843
THAP11 THAP domain containing 11 -4.09186
LYPLA1 lysophospholipase I -3.75303
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.72262
MSMO1 methylsterol monooxygenase 1 -3.39857
CAB39 calcium binding protein 39 -3.36677
PFKP phosphofructokinase, platelet -2.61631
TSPAN3 tetraspanin 3 -2.52035
UBL5 ubiquitin-like 5 -2.51704
MCM3 minichromosome maintenance complex component 3 -2.47311
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.43954
MSN moesin -2.32419
ICAM3 intercellular adhesion molecule 3 -2.31801
PGK1 phosphoglycerate kinase 1 -2.30704
SACS sacsin molecular chaperone -2.29368
SBNO1 strawberry notch homolog 1 (Drosophila) -2.27291
PTPN20 protein tyrosine phosphatase, non-receptor type 20 -2.23762
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.15292
TRAPPC8 trafficking protein particle complex 8 -2.15223
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -2.14396
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.1429
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.13232
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.12495
FZD7 frizzled class receptor 7 -2.12361
CUEDC2 CUE domain containing 2 -2.11536
AKIRIN1 akirin 1 -2.09505
CUTC cutC copper transporter -2.07349
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.0343
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.02072
CST7 cystatin F (leukocystatin) -2.01693
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.01619
URI1 URI1, prefoldin-like chaperone -2.01587
STX10 syntaxin 10 -2.01389
ATP5F1B ATP synthase F1 subunit beta -2.01064
ARID4B AT rich interactive domain 4B (RBP1-like) -2.00549
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -2.00178
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.00014