CRCGN015_MCF10A.WT.HP_24H:A05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.78787
CCL2 chemokine (C-C motif) ligand 2 3.60233
RPL39L ribosomal protein L39-like 3.50549
TIMP2 TIMP metallopeptidase inhibitor 2 3.39276
AKT1 v-akt murine thymoma viral oncogene homolog 1 3.34481
LGMN legumain 2.96172
BAD BCL2-associated agonist of cell death 2.90176
GRN granulin 2.45155
SPAG4 sperm associated antigen 4 2.40985
GATA3 GATA binding protein 3 2.29407
TXLNA taxilin alpha 2.17885
MAMLD1 mastermind-like domain containing 1 2.0811
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.06206
PRR7 proline rich 7 (synaptic) 2.04428

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -3.70974
PCNA proliferating cell nuclear antigen -3.64171
PUF60 poly-U binding splicing factor 60KDa -3.28806
THAP11 THAP domain containing 11 -3.20284
ARID4B AT rich interactive domain 4B (RBP1-like) -3.08565
RGS2 regulator of G-protein signaling 2 -2.96079
DIPK1A divergent protein kinase domain 1A -2.91074
KDM3A lysine (K)-specific demethylase 3A -2.45401
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.41458
RXYLT1 ribitol xylosyltransferase 1 -2.09611
CBR3 carbonyl reductase 3 -2.08517
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.08226
ILK integrin-linked kinase -2.02476