CRCGN015_MCF10A.WT.HP_24H:A06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

96 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.00622
GPER1 G protein-coupled estrogen receptor 1 3.91798
FGFR4 fibroblast growth factor receptor 4 3.31886
CAPN1 calpain 1, (mu/I) large subunit 3.17587
LOC107985101 uncharacterized LOC107985101 2.85799
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.79147
FBXL12 F-box and leucine-rich repeat protein 12 2.75387
WDR7 WD repeat domain 7 2.70012
NLGN4X neuroligin 4, X-linked 2.68134
SMIM40 small integral membrane protein 40 2.64402
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.61691
CNPY3 canopy FGF signaling regulator 3 2.48466
NBEA neurobeachin 2.48003
WIF1 WNT inhibitory factor 1 2.46388
SCN2A sodium channel, voltage gated, type II alpha subunit 2.45674
MRPL11 mitochondrial ribosomal protein L11 2.43731
COMP cartilage oligomeric matrix protein 2.43601
SOX17 SRY (sex determining region Y)-box 17 2.42425
RAB36 RAB36, member RAS oncogene family 2.38676
MEP1B meprin A, beta 2.37345
REG1B regenerating islet-derived 1 beta 2.36989
MTM1 myotubularin 1 2.30797
MATN2 matrilin 2 2.28087
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.27817
XDH xanthine dehydrogenase 2.27706
ZFTA zinc finger translocation associated 2.27064
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.267
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.23246
ZNF34 zinc finger protein 34 2.23221
DCAF4 DDB1 and CUL4 associated factor 4 2.22531
TNMD tenomodulin 2.22093
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.21943
ZG16 zymogen granule protein 16 2.20545
CCL15 chemokine (C-C motif) ligand 15 2.18895
LEP leptin 2.18085
ACVR2B activin A receptor, type IIB 2.18084
TXNL1 thioredoxin-like 1 2.16589
S1PR1 sphingosine-1-phosphate receptor 1 2.15746
HLA-DRA major histocompatibility complex, class II, DR alpha 2.14999
PCSK5 proprotein convertase subtilisin/kexin type 5 2.14621
STS steroid sulfatase (microsomal), isozyme S 2.1457
CRYBB3 crystallin, beta B3 2.14417
ISYNA1 inositol-3-phosphate synthase 1 2.13791
CRLF2 cytokine receptor-like factor 2 2.13674
AMHR2 anti-Mullerian hormone receptor, type II 2.13372
TBXA2R thromboxane A2 receptor 2.1333
DPT dermatopontin 2.1205
FBXL7 F-box and leucine-rich repeat protein 7 2.08859
RUNDC3B RUN domain containing 3B 2.08117
DHDDS dehydrodolichyl diphosphate synthase 2.06871
CDHR2 cadherin-related family member 2 2.06312
WNT6 wingless-type MMTV integration site family, member 6 2.06277
GUCA2A guanylate cyclase activator 2A (guanylin) 2.05431
PLIN1 perilipin 1 2.05318
GBX1 gastrulation brain homeobox 1 2.05058
GJA4 gap junction protein, alpha 4, 37kDa 2.04591
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.04042
GPA33 glycoprotein A33 (transmembrane) 2.03748
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 2.03414
GIMAP6 GTPase, IMAP family member 6 2.03293
MUC2 mucin 2, oligomeric mucus/gel-forming 2.03128
TKFC triokinase/FMN cyclase 2.0278
NEUROG1 neurogenin 1 2.02578
PIGR polymeric immunoglobulin receptor 2.02216
SART1 squamous cell carcinoma antigen recognized by T cells 2.02009
CLCN2 chloride channel, voltage-sensitive 2 2.01904
NOTCH4 notch 4 2.01396
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.01381
BMP3 bone morphogenetic protein 3 2.0089
CGRRF1 cell growth regulator with ring finger domain 1 2.008
NCS1 neuronal calcium sensor 1 2.00594
WSCD1 WSC domain containing 1 2.00121

decreased expression

Symbol Name Standardized Value
ETFB electron-transfer-flavoprotein, beta polypeptide -4.73475
OXA1L oxidase (cytochrome c) assembly 1-like -3.98184
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.96056
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.9146
ADI1 acireductone dioxygenase 1 -3.59149
KDM3A lysine (K)-specific demethylase 3A -3.46274
RNF167 ring finger protein 167 -3.04636
CD81 CD81 molecule -2.92541
MSN moesin -2.92434
MSMO1 methylsterol monooxygenase 1 -2.7834
WASHC4 WASH complex subunit 4 -2.65532
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.63621
GABARAP GABA(A) receptor-associated protein -2.44382
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.44131
TKT transketolase -2.33925
HOPX HOP homeobox -2.29879
RTRAF RNA transcription, translation and transport factor -2.28538
CAB39 calcium binding protein 39 -2.28316
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -2.20307
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.15732
ISCU iron-sulfur cluster assembly enzyme -2.06781
MEMO1 mediator of cell motility 1 -2.05754
BASP1 brain abundant, membrane attached signal protein 1 -2.01246
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.00496