| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | potassium 1h-indol-3-yl sulfate 34.76 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 6.94916 |
| UBQLN2 | ubiquilin 2 | 3.98456 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.94932 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.81596 |
| SPAG4 | sperm associated antigen 4 | 3.18815 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3.15191 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.86519 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.86169 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.83404 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.76662 |
| ACLY | ATP citrate lyase | 2.76444 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.74532 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.67694 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.61374 |
| TXNRD1 | thioredoxin reductase 1 | 2.53294 |
| ANKRD10 | ankyrin repeat domain 10 | 2.46988 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.41265 |
| IL1B | interleukin 1, beta | 2.3685 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.28471 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.28216 |
| RTN2 | reticulon 2 | 2.28177 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.26253 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.24951 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 2.24289 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 2.19691 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.19212 |
| IER3 | immediate early response 3 | 2.18724 |
| PDLIM1 | PDZ and LIM domain 1 | 2.1658 |
| UNC119 | unc-119 homolog (C. elegans) | 2.13675 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 2.13465 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.0993 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 2.08768 |
| NRIP1 | nuclear receptor interacting protein 1 | 2.07232 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.0682 |
| TSPAN6 | tetraspanin 6 | 2.0649 |
| TAC1 | tachykinin, precursor 1 | 2.05379 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 2.02544 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.00005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSMO1 | methylsterol monooxygenase 1 | -3.4775 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.21537 |
| NUP85 | nucleoporin 85kDa | -3.2092 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -3.15848 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -3.09001 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.07273 |
| SYPL1 | synaptophysin-like 1 | -3.00858 |
| VIM | vimentin | -2.90854 |
| UBE3C | ubiquitin protein ligase E3C | -2.79867 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.76003 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.68169 |
| RGS2 | regulator of G-protein signaling 2 | -2.66258 |
| CD81 | CD81 molecule | -2.66136 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.63865 |
| KLHDC2 | kelch domain containing 2 | -2.63053 |
| TEX10 | testis expressed 10 | -2.57235 |
| LYPLA1 | lysophospholipase I | -2.5708 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.5626 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.4769 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.37482 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -2.3291 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.32597 |
| MLH1 | mutL homolog 1 | -2.26822 |
| CCNB2 | cyclin B2 | -2.25516 |
| ADIPOR1 | adiponectin receptor 1 | -2.18863 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -2.16912 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.14499 |
| TMEM208 | transmembrane protein 208 | -2.14414 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.13771 |
| SAP30BP | SAP30 binding protein | -2.13095 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.11518 |
| EAPP | E2F-associated phosphoprotein | -2.06231 |
| CERS2 | ceramide synthase 2 | -2.04719 |
| MYO5C | myosin VC | -2.019 |
| TBCB | tubulin folding cofactor B | -2.01303 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | -2.01292 |
