CRCGN015_MCF10A.WT.HP_24H:A09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description potassium 1h-indol-3-yl sulfate 11.59 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.98083
CNRIP1 cannabinoid receptor interacting protein 1 4.97727
HMOX1 heme oxygenase 1 4.86076
ATP11B ATPase, class VI, type 11B 3.87674
CCDC92 coiled-coil domain containing 92 3.87263
NPDC1 neural proliferation, differentiation and control, 1 3.24499
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.17363
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.78659
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.73887
COMP cartilage oligomeric matrix protein 2.73815
ZNF589 zinc finger protein 589 2.43379
IL1B interleukin 1, beta 2.37126
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.3576
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.29208
CENPE centromere protein E, 312kDa 2.28198
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.23795
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.14195
TXNRD1 thioredoxin reductase 1 2.14185
TXNL4B thioredoxin-like 4B 2.10143
ABHD4 abhydrolase domain containing 4 2.07473
CAPN1 calpain 1, (mu/I) large subunit 2.05255
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.01475

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -5.14797
HMG20B high mobility group 20B -4.7939
DERA deoxyribose-phosphate aldolase (putative) -4.46484
TEX10 testis expressed 10 -4.38656
RGS2 regulator of G-protein signaling 2 -3.79601
THAP11 THAP domain containing 11 -2.89071
TM9SF2 transmembrane 9 superfamily member 2 -2.79868
KDM3A lysine (K)-specific demethylase 3A -2.47603
PTTG1IP pituitary tumor-transforming 1 interacting protein -2.33309
RDX radixin -2.08666
ALDOC aldolase C, fructose-bisphosphate -2.07625
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.06132