CRCGN015_MCF10A.WT.HP_24H:A10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 101.84 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SYNE2 spectrin repeat containing, nuclear envelope 2 5.2617
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.93686
AMDHD2 amidohydrolase domain containing 2 3.64319
CCDC92 coiled-coil domain containing 92 3.27253
CDCA4 cell division cycle associated 4 2.86406
C2CD2 C2 calcium-dependent domain containing 2 2.79596
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.69858
LGMN legumain 2.64089
MUC1 mucin 1, cell surface associated 2.48184
PRR7 proline rich 7 (synaptic) 2.36206
EAPP E2F-associated phosphoprotein 2.17854
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.11512
TRAF3 TNF receptor-associated factor 3 2.07479

decreased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.03964
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.91306
YME1L1 YME1-like 1 ATPase -3.80738
MRPS2 mitochondrial ribosomal protein S2 -3.62748
ACOT9 acyl-CoA thioesterase 9 -3.57555
FAIM Fas apoptotic inhibitory molecule -3.37326
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.87502
THAP11 THAP domain containing 11 -2.74662
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.61491
SHROOM2 shroom family member 2 -2.48406
APOO apolipoprotein O -2.35088
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.34523
PHEX phosphate regulating endopeptidase homolog, X-linked -2.24947
LHX2 LIM homeobox 2 -2.24123
ETFA electron-transfer-flavoprotein, alpha polypeptide -2.18075
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -2.14764
ASB8 ankyrin repeat and SOCS box containing 8 -2.10891
CEP70 centrosomal protein 70kDa -2.09233
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 -2.07099
CRAT carnitine O-acetyltransferase -2.0394