CRCGN015_MCF10A.WT.HP_24H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 11.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

42 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBX2 T-box 2 4.55762
EAPP E2F-associated phosphoprotein 4.52941
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.4317
KIF5C kinesin family member 5C 4.38942
CXCR4 chemokine (C-X-C motif) receptor 4 4.29774
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.95545
UGDH UDP-glucose 6-dehydrogenase 3.62968
AGR2 anterior gradient 2 3.21076
CAPN1 calpain 1, (mu/I) large subunit 2.35541
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.20805
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 2.18582
KLHL21 kelch-like family member 21 2.15719
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.15463
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.12824
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.12211
ARHGAP5 Rho GTPase activating protein 5 2.08409
HLX H2.0-like homeobox 2.06463
CD37 CD37 molecule 2.06431
LRRC8D leucine rich repeat containing 8 family, member D 2.06036
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.04571
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.03574

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.68396
MRPS2 mitochondrial ribosomal protein S2 -4.58918
HAT1 histone acetyltransferase 1 -4.36042
RNF167 ring finger protein 167 -4.20603
MTERF3 mitochondrial transcription termination factor 3 -3.59933
MSN moesin -3.52013
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.25272
CAB39 calcium binding protein 39 -2.99343
SEC16A SEC16 homolog A (S. cerevisiae) -2.99022
KDM3A lysine (K)-specific demethylase 3A -2.91636
MSMO1 methylsterol monooxygenase 1 -2.84657
PAEP progestagen-associated endometrial protein -2.82806
CAPN2 calpain 2, (m/II) large subunit -2.59923
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.36584
GNPAT glyceronephosphate O-acyltransferase -2.25288
PMPCA peptidase (mitochondrial processing) alpha -2.14079
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.10636
NELFB negative elongation factor complex member B -2.09786
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.03547
COQ4 coenzyme Q4 -2.01479
TUBB6 tubulin, beta 6 class V -2.01047