CRCGN015_MCF10A.WT.HP_24H:A15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 10.72 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.01756
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.82536
KDM5D lysine (K)-specific demethylase 5D 4.09695
ACAA1 acetyl-CoA acyltransferase 1 3.64771
HBA1 hemoglobin, alpha 1 3.58515
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.58148
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.47004
USP9Y ubiquitin specific peptidase 9, Y-linked 3.42302
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.04378
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.97952
TBX2 T-box 2 2.93795
BMP4 bone morphogenetic protein 4 2.86061
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.83865
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.7583
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.73957
HOOK2 hook microtubule-tethering protein 2 2.71396
TXNRD1 thioredoxin reductase 1 2.27192
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.1966
ECH1 enoyl CoA hydratase 1, peroxisomal 2.1664
AAMDC adipogenesis associated, Mth938 domain containing 2.10508
NLGN4Y neuroligin 4, Y-linked 2.06513

decreased expression

Symbol Name Standardized Value
MSN moesin -5.23579
DIPK1A divergent protein kinase domain 1A -4.24288
GOLT1B golgi transport 1B -3.93315
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.40712
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.1795
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.93688
SMC1A structural maintenance of chromosomes 1A -2.87062
RPA3 replication protein A3, 14kDa -2.58535
OCEL1 occludin/ELL domain containing 1 -2.48999
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.45166
SCYL3 SCY1-like 3 (S. cerevisiae) -2.33047
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.31577
ETNK1 ethanolamine kinase 1 -2.29273
HSPA1A heat shock 70kDa protein 1A -2.2224
PRSS3 protease, serine, 3 -2.20384
NCALD neurocalcin delta -2.17551
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -2.15793
ARID4B AT rich interactive domain 4B (RBP1-like) -2.15649
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.15481
PSAT1 phosphoserine aminotransferase 1 -2.11871
DCTN4 dynactin 4 (p62) -2.05314
UBA1 ubiquitin-like modifier activating enzyme 1 -2.03931
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.02836
TMEM187 transmembrane protein 187 -2.02395
THBS4 thrombospondin 4 -2.00133