CRCGN015_MCF10A.WT.HP_24H:A20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-[4-(5-nitro-2-furyl)-2-thiazo?lyl]formamide 32.78 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

78 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 5.15368
CRELD2 cysteine-rich with EGF-like domains 2 3.42115
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.32378
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.19793
CHEK1 checkpoint kinase 1 3.12287
SNX11 sorting nexin 11 3.03865
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.98861
UVRAG UV radiation resistance associated 2.75526
AAMDC adipogenesis associated, Mth938 domain containing 2.65136
LGMN legumain 2.56064
FSD1 fibronectin type III and SPRY domain containing 1 2.42131
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.39769
EPHB2 EPH receptor B2 2.35048
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.34231
PRMT7 protein arginine methyltransferase 7 2.33294
IL7 interleukin 7 2.25314
RANBP17 RAN binding protein 17 2.24467
KDM8 lysine (K)-specific demethylase 8 2.23343
L1TD1 LINE-1 type transposase domain containing 1 2.19594
ACAA1 acetyl-CoA acyltransferase 1 2.19588
PRR36 proline rich 36 2.18596
CADM1 cell adhesion molecule 1 2.16456
MRPL11 mitochondrial ribosomal protein L11 2.1543
TBX2 T-box 2 2.15403
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 2.15403
GHR growth hormone receptor 2.14589
NOTCH1 notch 1 2.13683
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 2.13116
PKN1 protein kinase N1 2.1292
RAP1GAP RAP1 GTPase activating protein 2.12247
TGFB3 transforming growth factor, beta 3 2.12076
HOXB5 homeobox B5 2.10216
ZFHX3 zinc finger homeobox 3 2.09201
STX4 syntaxin 4 2.0653
H2AB2 H2A.B variant histone 2 2.0652
LAMC3 laminin, gamma 3 2.02844
IRF3 interferon regulatory factor 3 2.00781

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -3.79183
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.72583
TM9SF3 transmembrane 9 superfamily member 3 -3.53948
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.44599
TM9SF2 transmembrane 9 superfamily member 2 -3.34298
KHDC4 KH domain containing 4, pre-mRNA splicing factor -3.12577
LDHD lactate dehydrogenase D -3.06552
RHOA ras homolog family member A -3.04587
IFRD2 interferon-related developmental regulator 2 -3.02072
TMEM230 transmembrane protein 230 -2.98364
CAB39 calcium binding protein 39 -2.90764
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.73275
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.70562
CRTAP cartilage associated protein -2.53517
ALDOC aldolase C, fructose-bisphosphate -2.51386
DSG2 desmoglein 2 -2.50072
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.4758
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.46021
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.43111
CASP8AP2 caspase 8 associated protein 2 -2.4303
MSN moesin -2.42117
IARS1 isoleucyl-tRNA synthetase 1 -2.38759
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.34182
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.3061
ANO10 anoctamin 10 -2.23598
IFNGR1 interferon gamma receptor 1 -2.2259
ENOPH1 enolase-phosphatase 1 -2.21845
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.2065
SNX5 sorting nexin 5 -2.17262
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -2.17163
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.14755
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -2.10517
ITPRID2 ITPR interacting domain containing 2 -2.09673
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.08851
FASTKD5 FAST kinase domains 5 -2.04944
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.04375
S100P S100 calcium binding protein P -2.03716
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.03517
SERINC1 serine incorporator 1 -2.03377
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.01787
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.01765