CRCGN015_MCF10A.WT.HP_24H:A22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 106.59 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

41 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ARID5B AT rich interactive domain 5B (MRF1-like) 3.35647
AMDHD2 amidohydrolase domain containing 2 3.05287
GSTZ1 glutathione S-transferase zeta 1 2.75685
AAMDC adipogenesis associated, Mth938 domain containing 2.53588
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.53583
CAPN1 calpain 1, (mu/I) large subunit 2.49815
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.46942
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.33349
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.29366
ANKRD10 ankyrin repeat domain 10 2.28296
CXCL14 chemokine (C-X-C motif) ligand 14 2.24832
WDR7 WD repeat domain 7 2.08233
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.06355
WIF1 WNT inhibitory factor 1 2.04465
TIAM1 T-cell lymphoma invasion and metastasis 1 2.02783
ARL4C ADP-ribosylation factor-like 4C 2.02137
GAB2 GRB2-associated binding protein 2 2.01302
CCL24 chemokine (C-C motif) ligand 24 2.00611
PTK2B protein tyrosine kinase 2 beta 2.00027

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.27001
CBR3 carbonyl reductase 3 -3.98429
KIF14 kinesin family member 14 -3.78466
NGRN neugrin, neurite outgrowth associated -3.36727
MRPS2 mitochondrial ribosomal protein S2 -3.16672
DERA deoxyribose-phosphate aldolase (putative) -2.79457
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.67643
SEC16A SEC16 homolog A (S. cerevisiae) -2.61856
BZW2 basic leucine zipper and W2 domains 2 -2.54523
OXA1L oxidase (cytochrome c) assembly 1-like -2.49621
BASP1 brain abundant, membrane attached signal protein 1 -2.46174
EDF1 endothelial differentiation-related factor 1 -2.3363
PCCB propionyl CoA carboxylase, beta polypeptide -2.32019
SMC1A structural maintenance of chromosomes 1A -2.3199
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.26151
CAB39 calcium binding protein 39 -2.23398
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.11713
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.113
KDM3A lysine (K)-specific demethylase 3A -2.10191
TSPAN3 tetraspanin 3 -2.08551
ALDOC aldolase C, fructose-bisphosphate -2.03897
MSMO1 methylsterol monooxygenase 1 -2.03538